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Cheng-Hao Wang
Researcher at Fudan University
Publications - 13
Citations - 524
Cheng-Hao Wang is an academic researcher from Fudan University. The author has contributed to research in topics: Metastasis & Epithelial–mesenchymal transition. The author has an hindex of 8, co-authored 12 publications receiving 361 citations. Previous affiliations of Cheng-Hao Wang include Chinese Ministry of Education.
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Journal ArticleDOI
miR-182-5p promotes hepatocellular carcinoma progression by repressing FOXO3a
Man-Qing Cao,Man-Qing Cao,A-Bin You,Xiao-Dong Zhu,Wei Zhang,Yuan-Yuan Zhang,Shi-Zhe Zhang,Ke‑Wei Zhang,Hao Cai,Wen-Kai Shi,Xiao-Long Li,Kang-Shuai Li,Dong-Mei Gao,De-Ning Ma,Bo-Gen Ye,Cheng-Hao Wang,Cheng-Dong Qin,Hui-Chuan Sun,Ti Zhang,Zhao-You Tang +19 more
TL;DR: It is shown that high expression of miR-182-5p in tumor tissues correlated with poor prognosis as well as early recurrence in HCC patients underwent curative surgery, and FOXO3a plays a key mediator in miR -182- 5p induced HCC progression.
Journal ArticleDOI
MicroRNA-26a suppresses epithelial-mesenchymal transition in human hepatocellular carcinoma by repressing enhancer of zeste homolog 2.
De-Ning Ma,Zong-Tao Chai,Xiao-Dong Zhu,Ning Zhang,Di-Hua Zhan,Bo-Gen Ye,Cheng-Hao Wang,Cheng-Dong Qin,Yiming Zhao,Weiping Zhu,Man-Qing Cao,Dong-Mei Gao,Hui-Chuan Sun,Zhao-You Tang +13 more
TL;DR: Down-regulation of miR-26a in HCCLM3 and HepG2 cells resulted in an EMT-like cell morphology and high motility in vitro and increased in tumor growth and pulmonary metastasis in vivo.
Journal ArticleDOI
CD31 regulates metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma via the ITGB1-FAK-Akt signaling pathway.
Yuanyuan Zhang,Ling Qun Kong,Xiao-Dong Zhu,Hao Cai,Cheng-Hao Wang,Wen Kai Shi,Man Qing Cao,Xiao Long Li,Kang Shuai Li,Shi-Zhe Zhang,Zong Tao Chai,Jian Yang Ao,Bo Gen Ye,Hui-Chuan Sun +13 more
TL;DR: The experiments show that CD31 promotes metastasis by inducing the epithelial-mesenchymal transition in hepatocellular carcinoma by up-regulating integrin β1 via the FAK/Akt signaling pathway.
Journal ArticleDOI
Colony-stimulating factor-1-induced AIF1 expression in tumor-associated macrophages enhances the progression of hepatocellular carcinoma
Hao Cai,Xiao-Dong Zhu,Jian Yang Ao,Bo Gen Ye,Yuan-Yuan Zhang,Zong Tao Chai,Cheng-Hao Wang,Wen Kai Shi,Man Qing Cao,Xiao-Long Li,Hui-Chuan Sun +10 more
TL;DR: In human HCC tissue, AIF1-positive macrophages in the adjacent microenvironment was associated with microvascular invasion and advanced TNM stages and with patients' overall and disease-free survival and the effects on tumor progression were evaluated by using in vitro and in vivo co-culture systems.
Journal Article
Postoperative adjuvant transcatheter arterial chemoembolization for resectable multiple hepatocellular carcinoma beyond the Milan criteria: a retrospective analysis
Zhao-Ru Dong,Peng-Fei Zhang,Cheng-Hao Wang,Chi Zhang,Jia-Bin Cai,Guo-Ming Shi,Ai-Wu Ke,Hui-Chuan Sun,Shuang-Jian Qiu,Jian Zhou,Jia Fan +10 more
TL;DR: The results show that postoperative adjuvant treatment resulted in delayed intrahepatic recurrence and better survival for patients with resectable multiple hepatocellular carcinoma beyond the Milan criteria.