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Hui-Chuan Sun
Researcher at Fudan University
Publications - 261
Citations - 13219
Hui-Chuan Sun is an academic researcher from Fudan University. The author has contributed to research in topics: Hepatocellular carcinoma & Internal medicine. The author has an hindex of 56, co-authored 227 publications receiving 10382 citations. Previous affiliations of Hui-Chuan Sun include Fudan University Shanghai Medical College & Government of the United States of America.
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Journal ArticleDOI
MicroRNA Expression, Survival, and Response to Interferon in Liver Cancer
Junfang Ji,Jiong Shi,Jiong Shi,Anuradha Budhu,Zhipeng Yu,Marshonna Forgues,Stephanie Roessler,Stefan Ambs,Yi Chen,Paul S. Meltzer,Carlo M. Croce,Lun Xiu Qin,Kwan Man,Chung Mau Lo,Joyce Man-Fong Lee,Irene Oi-Lin Ng,Jia Fan,Zhao-You Tang,Hui-Chuan Sun,Xin Wei Wang +19 more
TL;DR: The expression patterns of microRNAs in liver tissue differ between men and women with hepatocellular carcinoma, and the miR-26 expression status of such patients is associated with survival and response to adjuvant therapy with interferon alfa.
Journal ArticleDOI
Plasma MicroRNA Panel to Diagnose Hepatitis B Virus–Related Hepatocellular Carcinoma
Jian Zhou,Lei Yu,Xue Gao,Jie Hu,Jiping Wang,Zhi Dai,Jiefei Wang,Zhiyong Zhang,Shaohua Lu,Xiao-Wu Huang,Zheng Wang,Shuang-Jian Qiu,Xiaoying Wang,Guo-Huan Yang,Hui-Chuan Sun,Zhao-You Tang,Ying Wu,Hongguang Zhu,Jia Fan +18 more
TL;DR: A plasma microRNA panel that has considerable clinical value in diagnosing early-stage HCC is identified and patients who would have otherwise missed the curative treatment window can benefit from optimal therapy.
Journal ArticleDOI
High Expression of Macrophage Colony-Stimulating Factor in Peritumoral Liver Tissue Is Associated With Poor Survival After Curative Resection of Hepatocellular Carcinoma
Xiao-Dong Zhu,Ju-Bo Zhang,Peng-Yuan Zhuang,Hongguang Zhu,Wei Zhang,Yuquan Xiong,Wei-Zhong Wu,Lu Wang,Zhao-You Tang,Hui-Chuan Sun +9 more
TL;DR: High peritumoral M-CSF and M Phi were associated with HCC progression, disease recurrence, and poor survival after hepatectomy, highlighting the importance of peritUMoral tissue in the recurrence and metastasis of HCC.
Journal ArticleDOI
Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma
Ying Jiang,Aihua Sun,Yang Zhao,Yang Zhao,Wantao Ying,Hui-Chuan Sun,Xin-Rong Yang,Baocai Xing,Wei Sun,Liangliang Ren,Bo Hu,Li Chaoying,Li Zhang,Guangrong Qin,Menghuan Zhang,Ning Chen,Manli Zhang,Yin Huang,Zhou Jin'an,Yan Zhao,Mingwei Liu,Xiao-Dong Zhu,Yang Qiu,Yanjun Sun,Cheng Huang,Meng Yan,Mingchao Wang,Wei Liu,Fang Tian,Huali Xu,Jian Zhou,Zhenyu Wu,Tieliu Shi,Weimin Zhu,Jun Qin,Lu Xie,Jia Fan,Xiaohong Qian,Xiaohong Qian,Fuchu He +39 more
TL;DR: The proteomic stratification of early-stage hepatocellular carcinoma presented in this study provides insight into the tumour biology of this cancer, and suggests opportunities for personalized therapies that target it.
Journal ArticleDOI
A decade's studies on metastasis of hepatocellular carcinoma.
Zhao-You Tang,Sheng-Long Ye,Yinkun Liu,Lun-Xiu Qin,Hui-Chuan Sun,Qin-Hai Ye,Lu Wang,Jian Zhou,Shuang-Jian Qiu,Yan Li,Xue-Ning Ji,Hu Liu,Jing-Ling Xia,Zhi-Quan Wu,Jia Fan,Zeng-Chen Ma,Xin-Da Zhou,Zhi-Ying Lin,Kang-Da Liu +18 more
TL;DR: A molecular signature that can classify metastatic HCC patients is generated, osteopontin is identified as a lead gene in the signature, and it is found that genes favoring metastasis progression were initiated in the primary tumors.