C
Cheng-Lun Wu
Researcher at National Taiwan University
Publications - 6
Citations - 242
Cheng-Lun Wu is an academic researcher from National Taiwan University. The author has contributed to research in topics: Spermatogenesis & Internal medicine. The author has an hindex of 5, co-authored 5 publications receiving 225 citations.
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Journal ArticleDOI
Monascin and ankaflavin act as novel hypolipidemic and high-density lipoprotein cholesterol-raising agents in red mold dioscorea.
TL;DR: P purified monascin and ankaflavin, unlike monacolin K, were able to perform up-regulation rather than down-regulation on high-density lipoprotein cholesterol (HDL-C) levels in serum, explaining why RMD showed greater hypolipidemic and HDL-C-raising effect than RMR.
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Red Mold Rice Promotes Neuroprotective sAPPalpha Secretion Instead of Alzheimer’s Risk Factors and Amyloid Beta Expression in Hyperlipidemic Aβ40-Infused Rats
TL;DR: The neuroprotection provided by RMR downregulates Abeta40 formation and deposition by suppressing the cholesterol-raised beta-secretase activity and apolipoprotein E expression, as well as mediates the proteolytic process of APP toward neuroprotective sAPPalpha secretion in hippocampus.
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Red mold dioscorea has a greater antihypertensive effect than traditional red mold rice in spontaneously hypertensive rats.
TL;DR: A 1- fold RMD showed a greater antihypertensive effect than 1-fold RMR, and both RMR and RMD can improve the vascular elastin structure remodeling, suggesting that RMD has greater anti Hypertensive bioavailability.
Journal ArticleDOI
Synchronous high-performance liquid chromatography with a photodiode array detector and mass spectrometry for the determination of citrinin, monascin, ankaflavin, and the lactone and acid forms of monacolin K in red mold rice.
TL;DR: The results showed that high recovery rates of MKA, MKL, MS, AK, and CT are possible if RMR powder is extracted with 75% ethanol at 80 degrees C for 30 min and the optimal conditions of the HPLC can be clearly separated from any noise peaks.
Journal ArticleDOI
Immunomodulatory activities and antioxidant properties of polysaccharides from Monascus‐fermented products in vitro
Kuo-Chuan Tseng,Tony J Fang,Shen-Shih Chiang,Shen-Shih Chiang,Chin-Feng Liu,Cheng-Lun Wu,Tzu-Ming Pan +6 more
TL;DR: These findings demonstrate that RMRP and RMDP have antioxidant and immunomodulation potential to be developed as novel dietary supplements.