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Cheng Zhang

Researcher at Anhui Medical University

Publications -  125
Citations -  3561

Cheng Zhang is an academic researcher from Anhui Medical University. The author has contributed to research in topics: Placenta & Spermatogenesis. The author has an hindex of 33, co-authored 100 publications receiving 2715 citations.

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Melatonin alleviates cadmium-induced cellular stress and germ cell apoptosis in testes.

TL;DR: It is suggested that melatonin alleviates Cd‐induced cellular stress and germ cell apoptosis in testes and may be useful as pharmacological agents to protect against Cd-induced testicular toxicity.
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Cadmium-induced teratogenicity: association with ROS-mediated endoplasmic reticulum stress in placenta.

TL;DR: Antioxidants may be used as pharmacological agents to protect against Cd-induced fetal malformation and growth restriction and alpha-phenyl-N-t-butylnitrone, a free radical spin-trapping agent, significantly alleviated C d-induced placental ER stress and UPR.
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Maternal zinc deficiency during pregnancy elevates the risks of fetal growth restriction: a population-based birth cohort study

TL;DR: Maternal zinc deficiency during pregnancy elevates the risks of LBW and SGA infants and nuclear NF-κB p65 was significantly up-regulated in placentas of SGA cases as compared with controls.
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Endoplasmic reticulum stress is involved in hepatic SREBP-1c activation and lipid accumulation in fructose-fed mice.

TL;DR: Investigation of whether endoplasmic reticulum (ER) stress is mediated in the development of fructose-induced NAFLD found Phenylbutyric acid (PBA), an ER chemical chaperone, not only significantly attenuated ER stress, but also alleviated fructose- induced hepatic Insig-1 depletion.