C
Cheryl D. Horton
Researcher at Tufts University
Publications - 4
Citations - 92
Cheryl D. Horton is an academic researcher from Tufts University. The author has contributed to research in topics: Promoter & Gene. The author has an hindex of 4, co-authored 4 publications receiving 92 citations.
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Specific loss of protein kinase activities in senescent erythrocytes
TL;DR: The results show that aging erythrocytes undergo progressive loss of protein kinases that may adversely affect various cellular processes and the age-dependent loss of kinase activity reported here is one of the most striking manifestations of ERYthrocyte senescence yet to be reported.
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Neurotrophin-3 mediates the autocrine survival of the catecholaminergic CAD CNS neuronal cell line.
TL;DR: CAD cells possess an autocrine survival capability mediated by NT3, and may provide a valuable model system for studying the signaling pathways that mediate the actions of this little understood neurotrophin.
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Pituitary homeobox 1 (Pitx1) stimulates rat LHβ gene expression via two functional DNA-regulatory regions
TL;DR: Pitx1 stimulates the rat LHbeta gene promoter via two Pitx1 DNA-regulatory regions via two pituitary homeobox 1 sites, which further the understanding of the molecular mechanisms that regulate expression of this critical reproductive gene promoter.
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The orphan nuclear receptors COUP-TFI and COUP-TFII regulate expression of the gonadotropin LHβ gene
TL;DR: These data are the first to demonstrate COUP-TF expression and function in pituitary gonadotropes and two gonadotrope-derived cell lines and suggest multiple mechanisms by which this factor modulates LHβ gene expression.