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Chi-Yue Wu

Researcher at Academia Sinica

Publications -  17
Citations -  667

Chi-Yue Wu is an academic researcher from Academia Sinica. The author has contributed to research in topics: Crystallin & Snake venom. The author has an hindex of 11, co-authored 17 publications receiving 628 citations. Previous affiliations of Chi-Yue Wu include National Yang-Ming University & National Taiwan University.

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A modified protein precipitation procedure for efficient removal of albumin from serum

TL;DR: This work has been able to refine the albumin depletion protocols and establish a modified albumin removal method using trichloroacetic acid (TCA)/acetone, which may offer a rapid method for purifying serum albumin in large scale.
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Strategic shotgun proteomics approach for efficient construction of an expression map of targeted protein families in hepatoma cell lines.

TL;DR: Data was obtained which demonstrated that the expression proteomics data could be correlated with longer telomeric length in tumorigenic Hep3B and demonstrated how proteomic and biological investigation could be mutually substantiated in a productive cycle of hypothesis and pattern driven research.
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Soyasaponin-I-modified invasive behavior of cancer by changing cell surface sialic acids

TL;DR: Results showed that SsaI was implicated in the invasive behavior of tumor cells, suggesting that altered alpha2,3-sialylation pathway played a crucial role in the adhesion and tumor metastases.
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Proteomics of snake venoms from Elapidae and Viperidae families by multidimensional chromatographic methods.

TL;DR: The multidimensional chromatographic methods revealed specific differences in venom proteins intra‐species as well as between species and families and isolated proteins that may be unique for each species.
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Biomic study of human myeloid leukemia cells differentiation to macrophages using DNA array, proteomic, and bioinformatic analytical methods.

TL;DR: A bioinformatics program was developed, the Bulk Gene Search System (BGSS), to search for the functions of genes and proteins identified by cDNA microarrays and proteomics, which identified regulated proteins and genes and were classified into seven groups according to subcellular locations and functions.