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Chih-Jen Yang
Researcher at Kaohsiung Medical University
Publications - 108
Citations - 2514
Chih-Jen Yang is an academic researcher from Kaohsiung Medical University. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 25, co-authored 96 publications receiving 2058 citations. Previous affiliations of Chih-Jen Yang include Kaohsiung Medical University Chung-Ho Memorial Hospital.
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Journal ArticleDOI
Fucosyltransferase 8 as a functional regulator of nonsmall cell lung cancer
Chien-Yu Chen,Yi-Hua Jan,Yi-Hsiu Juan,Chih-Jen Yang,Ming-Shyan Huang,Chong-Jen Yu,Pan-Chyr Yang,Michael Hsiao,Tsui-Ling Hsu,Chi-Huey Wong +9 more
TL;DR: The expression of FUT8 is up-regulated in nonsmall cell lung cancer (NSCLC) and correlates with tumor metastasis, disease recurrence, and poor survival in patients with NSCLC, and the results of glycoproteomic and microarray analyses show that F UT8 globally modifies surface antigens, receptors, and adhesion molecules and is involved in the regulation of dozens of genes associated with malignancy.
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Gastro-intestinal metastasis of primary lung carcinoma: Clinical presentations and outcome
Chih-Jen Yang,Jhi-Jhu Hwang,Wang-Yi Kang,Inn-Wen Chong,Tung-Heng Wang,Chau-Chyun Sheu,Jong-Rung Tsai,Ming-Shyan Huang +7 more
TL;DR: Six patients with primary lung cancer demonstrated symptomatic gastro-intestinal metastasis and three patients with gastric metastasis were diagnosed via gastro-endoscopy while one with cecal involvement was diagnosed via colon fiberscopy.
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Impact of type 2 diabetes on manifestations and treatment outcome of pulmonary tuberculosis
Chao-Chuan Wang,Chih-Jen Yang,Huang-Chi Chen,Shih-Chang Chuang,Inn-Wen Chong,Jhi-Jhu Hwang,Ming-Shyang Huang +6 more
TL;DR: It is confirmed that clinical manifestations and chest radiographs of PTB patients associated with type 2 DM significantly depart from the typical presentation.
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Pyrogallol induces G2-M arrest in human lung cancer cells and inhibits tumor growth in an animal model.
Chih-Jen Yang,Chuan-Sheng Wang,Jen-Yu Hung,Hurng-Wern Huang,Yi-Chen Chia,Pei-Hui Wang,Ching-Feng Weng,Ming-Shyan Huang +7 more
TL;DR: Results suggest that pyrogallol can be developed as a promising anti-lung cancer drug particular for the non-small cell lung cancer (NSCLC).
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Oxidative and endoplasmic reticulum stress signaling are involved in dehydrocostuslactone-mediated apoptosis in human non-small cell lung cancer cells.
Jen-Yu Hung,Ya-Ling Hsu,Wen-Chiu Ni,Ying-Ming Tsai,Chih-Jen Yang,Po-Lin Kuo,Ming-Shyan Huang +6 more
TL;DR: DHE is demonstrated to be a novel anticancer agent for the treatment of non-small cell lung cancer, and is supported by animal studies which have shown a dramatic 50% reduction in tumor size after 28 days of treatment.