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Chinnakannu Panneerselvam
Researcher at University of Madras
Publications - 9
Citations - 669
Chinnakannu Panneerselvam is an academic researcher from University of Madras. The author has contributed to research in topics: Oxidative stress & Grape seed extract. The author has an hindex of 9, co-authored 9 publications receiving 638 citations.
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Rejuvenation of antioxidant system in central nervous system of aged rats by grape seed extract
TL;DR: It is demonstrated that grape seed extract enhanced the antioxidant status and decreased the incidence of free radical-induced lipid peroxidation in the central nervous system of aged rats.
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Age-related oxidative protein damages in central nervous system of rats: modulatory role of grape seed extract
TL;DR: It is demonstrated that grape seed extract enhanced the antioxidant status and decreased the incidence of free radical induced protein oxidation in aged rats thereby protecting the central nervous system from the reactive oxygen species.
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Modulatory role of grape seed extract on age-related oxidative DNA damage in central nervous system of rats.
TL;DR: It is revealed that grape seed extract has inhibiting effect on the accumulation of age-related oxidative DNA damages in spinal cord and in various brain regions such as cerebral cortex, striatum and hippocampus.
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Ascorbic acid and α-tocopherol as potent modulators of apoptosis on arsenic induced toxicity in rats
TL;DR: The present work evaluated the regulatory effect exerted by Vitamin C and Vitamin E upon the apoptotic process, which can be assessed by the presence of cells with apoptosis associated DNA breaks and characterize the role of TNF-α and caspase-3 in rats intoxicated with arsenic.
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Oxidative stress on mitochondrial antioxidant defense system in the aging process : Role of DL-α-lipoic acid and L-carnitine
TL;DR: Co-supplementation of lipoic acid with carnitine has a beneficial effect in reversing the age-related abnormalities seen in aging, which was associated with the decrease in free radical production and rise in antioxidant levels by Carnitine and lipaic acid, thereby lowering oxidative stress.