Showing papers in "Clinica Chimica Acta in 2005"

TL;DR: H-FABP not only proves to be an excellent early marker for cardiac injury in acute coronary syndromes, but also allows detection of minor myocardial injury in heart failure and unstable angina.

TL;DR: Nanotechnology-the creation and utilization of materials, devices, and systems through the control of matter on the nanometer-has been applied to molecular diagnostics and various other nanotechnologies for manipulation at nanoscale as well as nanobiosensors are reviewed.

TL;DR: A frequent biological monitoring of phthalates in body fluids and tissues would be highly advisable, both in helping physicians to perform health risk assessments for exposure in the general population and in guiding governments to provide regulations concerning the maximum allowed concentrations in the environment.

TL;DR: OVX induces oxidative stress in the femur bone of rats and enzymatic antioxidants like SOD, GPx, GST were decreased in ovariectomized animals when compared to sham-operated control rats.

TL;DR: These techniques can supplement current nonparametric statistical methods and should be included, where appropriate, in the armamentarium of data processing methodologies.

TL;DR: Ginger supplementation suppresses colon carcinogenesis in the presence of the procarcinogen DMH and significantly reduced circulating lipid peroxidation and significantly enhanced the enzymic and non-enzymic antioxidants as compared to unsupplemented DMH-treated rats.

TL;DR: This work discusses the polymorphisms of paraoxonase (PON1), a liver and serum enzyme that hydrolyzes a number of OP compounds, and its role in modulating the toxicity of OPs, and stresses the importance of determining PON1 status.

TL;DR: The data provide strong evidence that when CBG is inactivated or congenitally absent then more than 25% of the total cortisol appears in the free fraction with the remainder associated with albumin, which reflects a simple measure of functional corticosteroid-binding globulin.

TL;DR: The physiology of the endothelium is summarised and the mechanisms by which obesity, through the secretory products of adipose tissue, influences endothelial function are explained.

TL;DR: The diagnostic capacity of PCT is superior to that of CRP due to the close correlation between PCT levels and the severity of sepsis and outcome, and neopterin is very useful in the diagnosis of viral infection.

TL;DR: Oxidative stress may be involved in breast cancer and the increased activities of erythrocyte antioxidant enzymes may be a compensatory upregulation in response to the increased oxidative stress.

TL;DR: Among the 3 oils, sesame oil offers better protection over blood pressure, lipid profiles and lipid peroxidation and increases enzymatic and nonenzymatic antioxidants.

TL;DR: This review focuses on the multitude of patterns of drug-induced renal failure due to tubulointerstitial disease, including osmotic nephropathy, crystal nephtropathy, and acute nephrocalcinosis.

TL;DR: Since many factors such as the ALDH2*1 gene and ADH2*2 gene, daily drinking habits, exercise, and dehydration enhance the increase in plasma concentration of uric acid induced by ethanol, it is important to pay attention to these factors, as well as ingested ethanol volume, type of alcoholic beverage, and the administration of anti-hyperuricemic agents, to prevent and treat ethanol-induced hyperuricemia.

TL;DR: This HPLC method was comparable to IEC and could represent an alternative for amino acid analysis and was able to separate argininosuccinic acid, homocystine and allo-isoleucine, rare but clinically significant amino acids.

TL;DR: Combined treatment of tumor with EA and radiation enhances oxidative stress and cytotoxicity in tumor cells and protects normal cells against radiation damage, which may offer potential therapeutic benefit in cancer radiotherapy.

TL;DR: Serum ferritin levels are a good indicator of iron stores in the body and recent proteomics and molecular biology studies have shown that ferritIn levels in arteries are increased in diseased tissues, which further supports the link of ferrit in to CAD/MI.

TL;DR: Serum lipase is a more reliable diagnostic marker of AP than serum amylase and early transient hypertransaminasemia reliably predicts biliary etiology, while serum carbohydrate-deficient transferrin and trypsin may predict an alcoholic etiology.

TL;DR: The active components present in natural extracts like that of black tea can be very effective in perhaps reducing the extent of injury and in overcoming oxidant damage caused by exposure to environmental agents like pesticides.

TL;DR: The role of different regulatory mechanisms in cholesterol homeostasis in physiologic and neoplastic conditions with emphasis on intracellular content of cholesteryl esters is here reviewed.

TL;DR: This first quantitative evidence may be useful for the risk assessment of DEHP released from blood bags, as whole blood products in PVC bags had the highest DEHP levels compared to the other blood products.

TL;DR: Autoantibodies, and the antigens they recognise, are potentially valuable in the prediction and prevention respectively of type 1 diabetes as well as in the classification of autoimmune diabetes.

TL;DR: A rapid, reliable free T4 method employing isotope dilution tandem mass spectrometry that has a rapid turn-around-time vs the equilibrium dialysis procedure, with a chromatographic run time of 8 min per sample.

TL;DR: Assays using alpha-Gal activity for determination of Fabry disease in females have a high false-negative value and Screening for alpha- Gal A deficiency by means of whole blood spots should not be performed in a females.

TL;DR: Genetic testing for RP requires screening for a group of genes, and genetic testing for presymptomatic diagnosis of RP is controversial, because of the complexity in phenotype and genetics.

TL;DR: The genotypes of A/C in XPC exon 15, T/CIn XRCC3 exon 7 and A/A in XPD exon 10 studied were significantly different between BC group and control group in Chinese population.

TL;DR: This work simulates tumor growth by calculating the dynamics of individual cancer cells by integrating biological data and functional information into a unified community-based mathematical framework, which will be a tool for cancer modeling that will ultimately have basic research, therapeutic and educational value.

TL;DR: It is here shown that stathmin (Op18) becomes heavily phosphorylated in cancerous mantle cell lymphomas and that the progression of the disease can be followed by the progress of phosphorylation of Op18 and by the appearance of additional phosphorylate spots.

TL;DR: Exhaled breath condensate analysis is currently more reliable for relative measures than for determining absolute levels of inflammatory mediators, but several methodological issues need to be addressed before this technique can be considered in the clinical management of patients with COPD.

TL;DR: Lipid peroxidation has a deleterious effect on the semen quality and MDA is an index of lipidperoxidation which may be a diagnostic tool for the analysis of infertility in the asthenozoospermic patients.