Chris W. Pool

TL;DR: The present findings of somatostatin neuronal sex differences in the BSTc and its sex reversal in the transsexual brain clearly support the paradigm that in transsexuals sexual differentiation of the brain and genitals may go into opposite directions and point to a neurobiological basis of gender identity disorder.

TL;DR: In this article, the authors showed that glucocorticoids suppress both CRH and vasopressin (AVP) neurons in the human hypothalamus, which may have important consequences for neuroendocrinological mechanisms such as the disturbance of water balance during treatment as well as the immunological processes in the brain and the pathogenesis of the withdrawal syndrome after discontinuation of corticosteroid treatment.

TL;DR: By direct tissue isoelectric focusing of brain tissue, peptides were effectively eluted and separated from sections up to 100 μm thickness, which allowed the detection of small peptides with a detection limit of approximately 10 pg/section.

TL;DR: No supplementary loss of pigmented neurons in the locus coeruleus was found in patients with depression and AD, which resembles the situation in idiopathic depression, but is in contrast with earlier studies on depression in AD.

TL;DR: The results suggest that the assembly of cytochrome oxidase or the processing of its subunits may be impaired, and that a relatively large pool of inactive enzyme or precursors is limited to the neuronal somata.