C
Christiaan H. Righolt
Researcher at University of Manitoba
Publications - 65
Citations - 796
Christiaan H. Righolt is an academic researcher from University of Manitoba. The author has contributed to research in topics: Population & Vaccination. The author has an hindex of 12, co-authored 58 publications receiving 458 citations. Previous affiliations of Christiaan H. Righolt include Delft University of Technology & Leiden University Medical Center.
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Journal ArticleDOI
Effectiveness of BNT162b2 and mRNA-1273 covid-19 vaccines against symptomatic SARS-CoV-2 infection and severe covid-19 outcomes in Ontario, Canada: test negative design study.
Hannah Chung,Siyi He,Sharifa Nasreen,Maria E. Sundaram,Maria E. Sundaram,Sarah A Buchan,Sarah Wilson,Branson Chen,Andrew Calzavara,Deshayne B. Fell,Deshayne B. Fell,Deshayne B. Fell,Peter C. Austin,Peter C. Austin,Kumanan Wilson,Kumanan Wilson,Kevin L Schwartz,Kevin L Schwartz,Kevin A. Brown,Kevin A. Brown,Jonathan B. Gubbay,Nicole E. Basta,Salaheddin M. Mahmud,Christiaan H. Righolt,Lawrence W. Svenson,Shannon E. MacDonald,Naveed Z. Janjua,Mina Tadrous,Mina Tadrous,Mina Tadrous,Jeffrey C. Kwong +30 more
TL;DR: In this article, the effectiveness of mRNA covid-19 vaccines against symptomatic infection and severe outcomes (hospital admission or death) was investigated. But, the effectiveness was not as high as the BNT162b2 or mRNA-1273 vaccines.
Journal ArticleDOI
Dynamic chromosomal rearrangements in Hodgkin’s lymphoma are due to ongoing three-dimensional nuclear remodeling and breakage-bridge-fusion cycles
TL;DR: This is the first study to demonstrate nuclear remodeling and associated genomic instability leading to the generation of Reed-Sternberg cells of Hodgkin’s lymphoma, highlighting the relevance of nuclear architecture in cancer.
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Shattered and stitched chromosomes-chromothripsis and chromoanasynthesis-manifestations of a new chromosome crisis?
Christiaan H. Righolt,Sabine Mai +1 more
TL;DR: Why care should be taken in using the term chromothripsis and what evidence is lacking to support its use while describing complex rearrangements are discussed.
Journal ArticleDOI
Seasonal influenza vaccination in older people: A systematic review and meta-analysis of the determining factors.
George N. Okoli,Otto L T Lam,Florentin Racovitan,Viraj K Reddy,Christiaan H. Righolt,Christine J. Neilson,Ayman Chit,Ayman Chit,Edward W. Thommes,Edward W. Thommes,Ahmed M Abou-Setta,Salaheddin M. Mahmud +11 more
TL;DR: Several factors may determine SIV uptake and vaccination adherence among older people, and more studies are needed to provide a stronger evidence base for planning more effective influenza vaccination programs.
Journal ArticleDOI
Three-Dimensional Quantitative Imaging of Telomeres in Buccal Cells Identifies Mild, Moderate, and Severe Alzheimer's Disease Patients
Shubha Mathur,Aleksandra Glogowska,Elizabeth McAvoy,Christiaan H. Righolt,Christiaan H. Righolt,Jaclyn Rutherford,Cornelia Willing,Upama Banik,Myuri Ruthirakuhan,Sabine Mai,Angeles Garcia +10 more
TL;DR: Three-dimensional telomeric analysis of buccal cells of 82 Alzheimer's disease patients and cognitively normal age and gender-matched controls indicates that matched controls have significantly different 3D telomere profiles compared to mild, moderate, and severe AD patients.