C
Christina C. Leslie
Researcher at National Jewish Health
Publications - 2
Citations - 166
Christina C. Leslie is an academic researcher from National Jewish Health. The author has contributed to research in topics: Mitogen-activated protein kinase & Benzo(a)pyrene. The author has an hindex of 2, co-authored 2 publications receiving 164 citations.
Papers
More filters
Journal ArticleDOI
The mitogen-activated protein kinase pathway can mediate growth inhibition and proliferation in smooth muscle cells. Dependence on the availability of downstream targets.
Karin E. Bornfeldt,Jean S. Campbell,Hidenori Koyama,Gretchen M. Argast,Christina C. Leslie,Elaine W. Raines,Edwin G. Krebs,Russell Ross +7 more
TL;DR: The MAPK pathway mediates either proliferation or growth inhibition in human arterial SMCs depending on the availability of specific downstream enzyme targets.
Journal ArticleDOI
Activation of group IVC phospholipase A2 by polycyclic aromatic hydrocarbons induces apoptosis of human coronary artery endothelial cells
Patricia K. Tithof,Sean M. Richards,Mona Elgayyar,Fu-Minn Menn,Vijay M. Vulava,Larry D. McKay,John Sanseverino,Gary S. Sayler,Dawn E. Tucker,Christina C. Leslie,K. P. Lu,Kenneth S. Ramos +11 more
TL;DR: Analysis of aortas isolated from feral mice inhabiting the Superfund site showed increased PARP and caspase-3 cleavage when compared to reference mice, and data suggest that PAHs induce apoptosis of HCAECs via activation of group IVC PLA2.