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Christophe Milési

Researcher at University of Montpellier

Publications -  73
Citations -  1661

Christophe Milési is an academic researcher from University of Montpellier. The author has contributed to research in topics: Medicine & Intensive care. The author has an hindex of 18, co-authored 57 publications receiving 1276 citations.

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High flow nasal cannula (HFNC) versus nasal continuous positive airway pressure (nCPAP) for the initial respiratory management of acute viral bronchiolitis in young infants: a multicenter randomized controlled trial (TRAMONTANE study)

TL;DR: In young infants with moderate to severe AVB, initial management with HFNC did not have a failure rate similar to that of nCPAP, and the success rate with the alternative respiratory support, intubation rate, durations of noninvasive and invasive ventilation, skin lesions, and length of PICU stay were comparable between groups.
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Is treatment with a high flow nasal cannula effective in acute viral bronchiolitis? A physiologic study.

TL;DR: HFNC with a flow rate equal to or above 2 L/kg/min generated a clinically relevant PP, with improved breathing pattern and rapid unloading of respiratory muscles, in young infants with acute RSV bronchiolitis.
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High-flow nasal cannula: recommendations for daily practice in pediatrics

TL;DR: The use of nasal cannula adapted to the infant’s nares size to deliver heated and humidified gas at high flow rates has been associated with improvements in washout of nasopharyngeal dead space, lung mucociliary clearance, and oxygen delivery compared with other oxygen delivery systems.
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Nasal continuous positive airway pressure decreases respiratory muscles overload in young infants with severe acute viral bronchiolitis

TL;DR: In young infants with severe acute respiratory syncytial virus bronchiolitis, nCPAP rapidly unloads respiratory muscles and improves respiratory distress symptoms, and a significant correlation was observed between the respiratory distress score and Pes swings at baseline and after n CPAP.
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6 cmH2O continuous positive airway pressure versus conventional oxygen therapy in severe viral bronchiolitis: a randomized trial.

TL;DR: The effects of nasal continuous positive airway pressure (nCPAP) and conventional oxygen therapy on the clinical signs of respiratory distress and the respiratory muscle workload in acute viral bronchiolitis are compared.