C
Christopher J. Morris
Researcher at University of East Anglia
Publications - 38
Citations - 1771
Christopher J. Morris is an academic researcher from University of East Anglia. The author has contributed to research in topics: PEGylation & Pulmonary Absorption. The author has an hindex of 18, co-authored 36 publications receiving 1526 citations. Previous affiliations of Christopher J. Morris include Cardiff University & Science and Technology Facilities Council.
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Journal ArticleDOI
Thrombogenic activity of doxorubicin in myeloma patients receiving thalidomide: implications for therapy
Maurizio Zangari,Eric R. Siegel,Bart Barlogie,Elias Anaissie,Fariba Saghafifar,Athanasios Fassas,Christopher J. Morris,Louis M. Fink,Guido Tricot +8 more
TL;DR: A statistical association between the incidence of DVT and combination chemotherapy including doxorubicin was observed and this association was confirmed on multivariate analysis.
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Evaluating the antioxidant potential of new treatments for inflammatory bowel disease using a rat model of colitis.
A D Millar,D. S. Rampton,C. L. Chander,A. W. D. Claxson,S. Blades,A. Coumbe,J. Panetta,Christopher J. Morris,D. R. Blake +8 more
TL;DR: The similarity of the chemiluminescence responses of colonic biopsy specimens from acetic acid induced colitis and ulcerative colitis to a range of conventional antioxidants and standard treatments suggests that this model is a useful method for testing the antioxidant potential of new therapies for inflammatory bowel disease.
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Synthesis and characterization of biocompatible thermo-responsive gelators based on ABA triblock copolymers.
Chengming Li,Yiqing Tang,Steven P. Armes,Christopher J. Morris,Susanna F. Rose,Andrew W. Lloyd,Andrew L. Lewis +6 more
TL;DR: These novel triblock copolymers are water-soluble in dilute aqueous solution at 20 degrees C and pH 7.4 but form free-standing physical gels at 37 degrees C due to hydrophobic interactions between the poly(N-isopropylacrylamide) blocks; this suggests possible applications in drug delivery and tissue engineering.
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Myeloma of the central nervous system: association with high-risk chromosomal abnormalities, plasmablastic morphology and extramedullary manifestations.
Athanasios Fassas,Firas Muwalla,Tanya Berryman,Riad Benramdane,Lija Joseph,Elias Anaissie,Rajesh Sethi,Raman Desikan,David S. Siegel,Ashraf Badros,Amir A. Toor,Maurizio Zangari,Christopher J. Morris,Edgardo J. Angtuaco,Sajini Mathew,Carla S. Wilson,Aubrey J. Hough,Sami I. Harik,Bart Barlogie,Guido Tricot +19 more
TL;DR: The characteristics of patients diagnosed and treated at the University of Arkansas over the last 10 years revealed association of CNS involvement with unfavourable cytogenetic abnormalities, high tumour mass, plasmablastic morphology, additional extramedullary myeloma manifestations and circulating plasma cells.
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Activated protein C resistance in the absence of factor V Leiden mutation is a common finding in multiple myeloma and is associated with an increased risk of thrombotic complications.
Maurizio Zangari,Fariba Saghafifar,Elias Anaissie,Ashraf Z. Badros,Raman Desikan,A. Fassas,P. Mehta,Christopher J. Morris,Amir A. Toor,D. Whitfield,Eric R. Siegel,Bart Barlogie,Louis Fink,Guido Tricot +13 more
TL;DR: Acquired APC resistance was present in almost one-quarter of newly diagnosed multiple myeloma patients and significantly increased the risk of deep venous thrombosis (DVT), in this series.