C
Christopher S. Straub
Researcher at Emory University
Publications - 15
Citations - 321
Christopher S. Straub is an academic researcher from Emory University. The author has contributed to research in topics: Cycloaddition & Diazo. The author has an hindex of 7, co-authored 15 publications receiving 307 citations.
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An Isomünchnone-Based Method for the Synthesis of Highly Substituted 2(1H)-Pyridones
TL;DR: In this article, a diazo transfer of 1-(benzenesulfonyl-diazoacetyl)-pyrrolidin-2-one with p-acetamidobenzenes sulfonyl azide and triethylamine was used for the synthesis of indolizidine alkaloid (±)-ipalbidine.
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Synthesis of the Angiotensin Converting Enzyme Inhibitor (−)-A58365A via an Cycloaddition Reaction
TL;DR: The angiotensin converting enzyme inhibitor (−)-A58365A (1) was synthesized by a process based on the [3 + 2]-cycloaddition reaction of a phenylsulfonyl-substituted intermediate as mentioned in this paper.
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Halo substituent effects on intramolecular cycloadditions involving furanyl amides.
TL;DR: Intramolecular Diels-Alder reactions involving a series of N-alkenyl-substituted furanyl amides were investigated, and stable functionalized oxanorbornenes were formed in high yield upon heating at 80-110 degrees C.
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Cycloaddition-Rearrangement Sequence of 2-Amido Substituted Furans as a Method of Synthesizing Hexahydroindolinones.
TL;DR: A convenient synthesis of various substituted hexahydroindolinones has been achieved by an intramolecular Diels-Alder cycloaddition (IMDAF) reaction of 2-amido substituted furans, which has the sidearm of the tethered alkenyl group oriented syn with respect to the oxygen bridge.
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Synthesis of furo[3,4-c]furans using a rhodium(II)-catalyzed cyclization/Diels-Alder cycloaddition sequence.
TL;DR: The Rh(II)-catalyzed cyclization reaction was quite versatile with regard to the nature of the interacting carbonyl group and was applied to the synthesis of several oxa-polyheterocyclic systems by first generating a 2-alkoxy-substituted furan and then allowing it to undergo a subsequent intramolecular Diels-Alder cycloaddition.