C
Chuan Qin
Researcher at Scripps Research Institute
Publications - 6
Citations - 2713
Chuan Qin is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Metabolite & Mass spectrometry. The author has an hindex of 6, co-authored 6 publications receiving 2388 citations.
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Journal ArticleDOI
METLIN: a metabolite mass spectral database.
Colin A. Smith,Grace O'Maille,Elizabeth J. Want,Chuan Qin,Sunia A. Trauger,Theodore R. Brandon,Darlene E. Custodio,Ruben Abagyan,Gary Siuzdak +8 more
TL;DR: METLIN includes an annotated list of known metabolite structural information that is easily cross-correlated with its catalogue of high-resolution Fourier transform mass spectrometry (FTMS) spectra, tandem mass spectrumetry (MS/MS) Spectra, and LC/MS data.
Journal ArticleDOI
Solvent-dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry.
Elizabeth J. Want,Grace O'Maille,Colin A. Smith,Theodore R. Brandon,Wilasinee Uritboonthai,Chuan Qin,Sunia A. Trauger,Gary Siuzdak +7 more
TL;DR: Novel data analysis software, XCMS, was used to monitor all metabolite features detected from an array of serum extraction methods, with application to metabolite profiling using electrospray liquid chromatography/mass spectrometry (ESI-LC/MS).
Journal ArticleDOI
Nonlinear data alignment for UPLC-MS and HPLC-MS based metabolomics: quantitative analysis of endogenous and exogenous metabolites in human serum.
TL;DR: UPLC displayed better retention time reproducibility and signal-to-noise ratios for spiked compounds over HPLC, making this technology more suitable for nontargeted metabolomics applications.
A Metabolite Mass Spectral Database
Colin A. Smith,Elizabeth J. Want,Chuan Qin,Sunia A. Trauger,Theodore R. Brandon,Darlene E. Custodio,Ruben Abagyan,Gary Siuzdak +7 more
TL;DR: METLIN includes an annotated list of known metabolite structural information that is easily cross-correlated with its catalogue of high-resolution Fourier transform mass spectrometry (FTMS) spectra, tandem mass spectrumetry (MS/MS) Spectra, and LC/MS data.
Journal ArticleDOI
Phospholipid capture combined with non-linear chromatographic correction for improved serum metabolite profiling
TL;DR: Application of phospholipid capture in combination with XCMS non-linear data processing has enormous potential in metabolite profiling, for biomarker detection and quantitation.