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Gary Siuzdak

Researcher at Scripps Research Institute

Publications -  293
Citations -  36950

Gary Siuzdak is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Mass spectrometry & Metabolomics. The author has an hindex of 81, co-authored 280 publications receiving 31641 citations. Previous affiliations of Gary Siuzdak include Baylor College of Medicine & Washington University in St. Louis.

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Journal ArticleDOI

XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification.

Colin A. Smith, +4 more
- 07 Jan 2006 - 
TL;DR: An LC/MS-based data analysis approach, XCMS, which incorporates novel nonlinear retention time alignment, matched filtration, peak detection, and peak matching, and is demonstrated using data sets from a previously reported enzyme knockout study and a large-scale study of plasma samples.
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Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

William R. Wikoff, +6 more
- 10 Mar 2009 - 
TL;DR: A broad, drug-like phase II metabolic response of the host to metabolites generated by the microbiome was observed, suggesting that the gut microflora has a direct impact on the drug metabolism capacity of theHost.
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METLIN: a metabolite mass spectral database.

Colin A. Smith, +8 more
- 01 Dec 2005 - 
TL;DR: METLIN includes an annotated list of known metabolite structural information that is easily cross-correlated with its catalogue of high-resolution Fourier transform mass spectrometry (FTMS) spectra, tandem mass spectrumetry (MS/MS) Spectra, and LC/MS data.
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Innovation: Metabolomics: the apogee of the omics trilogy

Gary J. Patti, +2 more
- 22 Mar 2012 - 
TL;DR: By performing global metabolite profiling, also known as untargeted metabolomics, new discoveries linking cellular pathways to biological mechanism are being revealed and are shaping the understanding of cell biology, physiology and medicine.
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Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins

Hongyan Zhou, +13 more
- 08 May 2009 - 
TL;DR: It is confirmed that beating cardiomyocytes Differentiated from piPSCs results in cells that secrete ATP, a substance that can be converted into ATP by the immune system through cell reprograming.