C
Chun-Fu Lai
Researcher at National Taiwan University
Publications - 79
Citations - 2839
Chun-Fu Lai is an academic researcher from National Taiwan University. The author has contributed to research in topics: Dialysis & Acute kidney injury. The author has an hindex of 29, co-authored 70 publications receiving 2408 citations. Previous affiliations of Chun-Fu Lai include Washington University in St. Louis & Memorial Hospital of South Bend.
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Journal ArticleDOI
Long-Term Risk of Coronary Events after AKI
Vin-Cent Wu,Che-Hsiung Wu,Tao-Min Huang,Cheng-Yi Wang,Chun-Fu Lai,Chih-Chung Shiao,Chia-Hsui Chang,Shuei-Liong Lin,Yen-Yuan Chen,Yung-Ming Chen,Tzong-Shinn Chu,Wen-Chih Chiang,Kwan-Dun Wu,Pi-Ru Tsai,Likwang Chen,Wen-Je Ko +15 more
TL;DR: The results reveal that AKI with recovery associated with higher long-term risks of coronary events and death in this cohort is suggested, suggesting thatAKI may identify patients with high risk of future coronary events.
Journal ArticleDOI
Transforming Growth Factor β-1 Stimulates Profibrotic Epithelial Signaling to Activate Pericyte-Myofibroblast Transition in Obstructive Kidney Fibrosis
Ching Fang Wu,Wen-Chih Chiang,Chun-Fu Lai,Fan-Chi Chang,Yi-Ting Chen,Yu-Hsiang Chou,Ting Hui Wu,Geoffrey Linn,Hong Ling,Kwan-Dun Wu,Tun-Jun Tsai,Yung-Ming Chen,Jeremy S. Duffield,Shuei-Liong Lin +13 more
TL;DR: A novel link between injured epithelium and pericyte-myofibroblast transition through TGF-β1 during kidney fibrosis is identified.
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Acute-on-chronic kidney injury at hospital discharge is associated with long-term dialysis and mortality
Vin-Cent Wu,Tao-Min Huang,Chun-Fu Lai,Chih-Chung Shiao,Yu-Feng Lin,Tzong-Shinn Chu,Pei-Chen Wu,Chia-Ter Chao,Jann-Yuan Wang,Tze-Wah Kao,Guang-Huar Young,Pi-Ru Tsai,Hung-Bin Tsai,Chieh-Li Wang,Ming-Shou Wu,Wen-Chih Chiang,I-Jung Tsai,Fu-Chang Hu,Shuei-Liong Lin,Yung-Ming Chen,Tun-Jun Tsai,Wen-Je Ko,Kwan-Dun Wu +22 more
TL;DR: In a large cohort of postoperative patients who developed AKI, those with existing CKD were at higher risk for long-term mortality and dialysis after hospital discharge than those without and outcomes were significantly worse in those with unresolved AKI at discharge.
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Pentoxifylline Attenuates Tubulointerstitial Fibrosis by Blocking Smad3/4-Activated Transcription and Profibrogenic Effects of Connective Tissue Growth Factor
Shuei-Liong Lin,Ruey-Hwa Chen,Yung-Ming Chen,Wen-Chih Chiang,Chun-Fu Lai,Kwan-Dun Wu,Tun-Jun Tsai +6 more
TL;DR: Results indicate that PTX inhibits CTGF expression by interfering with Smad3/4-dependent CTGF transcription through protein kinase A and blocks the profibrogenic effects of CTGF on renal cells.
Journal ArticleDOI
Sleep disturbance in chronic hemodialysis patients: the impact of depression and anemia.
TL;DR: The data indicate that in the management of insomnia in this patient group, anemia and depression, both of which are potentially correctable, should be assessed.