Chunjie Wu

TL;DR: As an important herbal medicine, A. catechu has potential for the treatment of many diseases, especially parasitic diseases, digestive function disorders, and depression, and further research should be undertaken to investigate the clinical effects, toxic constituents, target organs, and pharmacokinetics.

TL;DR: Despite continued progress in research on various aspects of natural agents exerting protective effects against EC injury by activating Nrf2/HO-1 signaling, the development of new drugs for the treatment of atherosclerosis and other CVDs based on these agents will require more detailed preclinical and clinical studies.

TL;DR: Many traditional usages of this plant have been validated by present investigations, however, further research elucidating the structure-function relationship among chemical compounds, understanding the mechanism of unique sensation, as well as exploring new clinical effects and establishing criteria for quality control for Z. bungeanum should be further studied.

TL;DR: Arecoline has great potential to be a therapeutic drug for various ailments, however, further investigations are needed in the future to reduce or eliminate its toxicities before developing into new drug.

TL;DR: The present review will highlight the importance of herbal medicines and its components for treating RA via induction of apoptosis in FLS, and provide some directions for the future development of these mentioned herbal medicines as anti-RA drugs in clinical.