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Cinzia M. Bellettato
Researcher at University of Ferrara
Publications - 11
Citations - 2307
Cinzia M. Bellettato is an academic researcher from University of Ferrara. The author has contributed to research in topics: COPD & ICAM-1. The author has an hindex of 9, co-authored 9 publications receiving 2168 citations. Previous affiliations of Cinzia M. Bellettato include Imperial College London & University of Modena and Reggio Emilia.
Papers
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Journal ArticleDOI
Infections and airway inflammation in chronic obstructive pulmonary disease severe exacerbations.
Alberto Papi,Cinzia M. Bellettato,Fausto Braccioni,Micaela Romagnoli,Paolo Casolari,Gaetano Caramori,Leonardo M. Fabbri,Sebastian L. Johnston +7 more
TL;DR: Respiratory infections are associated with the majority of COPD exacerbations and their severity, especially those with viral/bacterial coinfection, and airway neutrophilia is related to exacerbation severity regardless of viral and/or bacterial infections.
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The C-C chemokine receptors CCR4 and CCR8 identify airway T cells of allergen-challenged atopic asthmatics
Paola Panina-Bordignon,Alberto Papi,Margherita Mariani,Pietro Di Lucia,Gianluca Casoni,Cinzia M. Bellettato,Cecilia Buonsanti,Deborah Miotto,Cristina E. Mapp,Antonello Villa,Gianluigi Arrigoni,Leonardo M. Fabbri,Francesco Sinigaglia +12 more
TL;DR: Investigation of the expression of chemokines and chemokine receptors in the airway mucosa of atopic asthmatics suggests that CCR4, of its ligands MDC and TARC, and of CCR8 could be considered as targets for therapeutic intervention.
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Increased Expression of the Chemokine Receptor CXCR3 and Its Ligand CXCL10 in Peripheral Airways of Smokers with Chronic Obstructive Pulmonary Disease
Marina Saetta,M. Mariani,Paola Panina-Bordignon,Graziella Turato,Cecilia Buonsanti,Simonetta Baraldo,Cinzia M. Bellettato,Alberto Papi,Lorenzo Corbetta,Renzo Zuin,Francesco Sinigaglia,Leonardo M. Fabbri +11 more
TL;DR: The findings suggest that the CXCR3/CXCL10 axis may be involved in the T cell recruitment that occurs in peripheral airways of smokers with COPD and that these T cells may have a type-1 profile.
Journal ArticleDOI
Nuclear localisation of p65 in sputum macrophages but not in sputum neutrophils during COPD exacerbations
Gaetano Caramori,Micaela Romagnoli,Paolo Casolari,Cinzia M. Bellettato,G Casoni,Piera Boschetto,Kian Fan Chung,Peter J. Barnes,Ian M. Adcock,Adalberto Ciaccia,Leonardo M. Fabbri,Alberto Papi +11 more
TL;DR: NF-kappaB appears to be activated in sputum macrophages but not in spUTum neutrophils during exacerbations of COPD, as measured by immunocytochemistry and nuclear staining for p65.
Journal ArticleDOI
Expression of Programmed Death–1 Ligand (PD-L) 1, PD-L2, B7-H3, and Inducible Costimulator Ligand on Human Respiratory Tract Epithelial Cells and Regulation by Respiratory Syncytial Virus and Type 1 and 2 Cytokines
Luminita A. Stanciu,Cinzia M. Bellettato,Cinzia M. Bellettato,Vasile Laza-Stanca,Anthony J. Coyle,Alberto Papi,Sebastian L. Johnston +6 more
TL;DR: Respiratory tract epithelial cells express a wide range of B7 molecules, and this expression is differentially regulated by IFN-gamma and IL-4, which may be involved in decreasing T cell antiviral immune responses to RSV and in RSV-associated wheezing.