Clara Sousa

TL;DR: A systematic review on infrared spectroscopy applications for bacterial typing, highlighting fundamental aspects of infraredSpectroscopy, a detailed literature review (covering different taxonomic levels and bacterial species), advantages, and limitations of the technique over molecular biology methods and a comparison with other competing spectroscopic techniques.

TL;DR: This work successfully developed an approach that combines MALDI-TOF MS and chemometric tools to discriminate the six Acb complex species and led to 100% of correct species identification using mass spectra obtained from intact cells.

TL;DR: It is demonstrated, for the first time, that characteristic mass fingerprints of different E. coli HiRCC are sufficiently discriminatory and robust to enable their differentiation by MALDI-TOF MS, which might represent a promising tool for the optimisation of infection control, individual patient management and large-scale epidemiological studies of public health relevance.

TL;DR: The suitability of MALDI-TOF-MS combined with chemometrics to accurately and rapidly identify Bacillus pumilus and B. safensis isolates was demonstrated, allowing their reliable, reproducible and rapid identification.

TL;DR: Good agreement between experimental and theoretical data was achieved, and some correlations between structure and energy were made, and the aromaticity of the compounds was evaluated by the nucleus independent chemical shifts (NICS).