Claudia Fragiacomo

TL;DR: Findings suggest that relative folate deficiency may precede AD and VaD onset and Hyperhomocysteinemia might also be an early risk factor for cognitive decline in the elderly, but its role in dementia development must be addressed in future longitudinal studies.

TL;DR: In this paper, the presence and source of pro and anti- inflammatory cytokines in the blood of patients with Alzheimer's disease (AD), multi-infarct dementia (MID) or in non-demented elderly people (controls) were evaluated.

TL;DR: Reanalysis results suggest that subclinical folate deficiency and hyperhomocysteinemia might predate dementia onset, findings to be confirmed by longitudinal studies.

TL;DR: The results show that patients with Alzheimer disease or multiinfarct dementia have an upregulation of circulating cytokines and a downregulation of cytokines released by blood cells.

TL;DR: Apolipoprotein E genotypes, presenilin 1 (PS-1) and α1-antichymotrypsin (ACT) polymorphism and the association of the genotypes were examined in patients with Alzheimer’s disease or vascular dementia and indicate an increase in ApoE ε4 in Vd, too.