C
Claudia L. Hofstra
Researcher at Johnson & Johnson Pharmaceutical Research and Development
Publications - 3
Citations - 896
Claudia L. Hofstra is an academic researcher from Johnson & Johnson Pharmaceutical Research and Development. The author has contributed to research in topics: Histamine H1 receptor & Histamine. The author has an hindex of 3, co-authored 3 publications receiving 867 citations.
Papers
More filters
Journal ArticleDOI
Histamine H4 Receptor Mediates Chemotaxis and Calcium Mobilization of Mast Cells
TL;DR: In this paper, it was shown that histamine induces chemotaxis of mouse mast cells, without affecting mast cell degranulation, and that activation of H4 receptors by histamine resulted in calcium mobilization from intracellular calcium stores.
Journal ArticleDOI
A Potent and Selective Histamine H4 Receptor Antagonist with Anti-Inflammatory Properties
Robin L. Thurmond,Pragnya J. Desai,Paul J. Dunford,Wai-Ping Fung-Leung,Claudia L. Hofstra,Wen Jiang,Steven Nguyen,Jason P. Riley,Siquan Sun,Kacy N. Williams,James P. Edwards,Lars Karlsson +11 more
TL;DR: The results indicate that the histamine H4 receptor plays a role in the inflammatory process and may have the potential to be useful in treating inflammation in humans.
Journal ArticleDOI
Tbt-1, a new T-box transcription factor induced in activated Th1 and CD8+ T cells
TL;DR: Tb-1 is the first T-box transcription factor shown to be specific for Th1 cell differentiation, and phylogenetic analyses indicate that Tbt-1 co-evolved with adaptive immune responses.