C
Clyde E. Hart
Researcher at Centers for Disease Control and Prevention
Publications - 42
Citations - 4125
Clyde E. Hart is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Virus & Population. The author has an hindex of 25, co-authored 42 publications receiving 3881 citations.
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Journal ArticleDOI
Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana.
Michael C. Thigpen,Poloko Kebaabetswe,Lynn A. Paxton,Dawn K. Smith,Charles E. Rose,Tebogo M. Segolodi,Faith L. Henderson,Sonal R Pathak,Fatma A. Soud,Kata Chillag,Rodreck Mutanhaurwa,Lovemore Ian Chirwa,Michael Kasonde,Daniel Abebe,Evans Buliva,Roman Gvetadze,Sandra H. Johnson,Thom Sukalac,Vasavi Thomas,Clyde E. Hart,Jeffrey A. Johnson,C. Kevin Malotte,Craig W. Hendrix,John T. Brooks +23 more
TL;DR: Daily TDF-FTC prophylaxis prevented HIV infection in sexually active heterosexual adults and had a significant decline in bone mineral density, which remains unknown.
Journal ArticleDOI
Correlation of Human Immunodeficiency Virus Type 1 RNA Levels in Blood and the Female Genital Tract
Clyde E. Hart,Jeffrey L. Lennox,Melody Pratt-Palmore,Thomas C. Wright,Raymond F. Schinazi,Tammy Evans-Strickfaden,Timothy J. Bush,Cathy Schnell,Lois Conley,Kelly A. Clancy,Tedd V. Ellerbrock +10 more
TL;DR: Factors that lower blood plasma virus load may also reduce the risk of perinatal and female-to-male heterosexual transmission by lowering vaginal virus load.
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Long-Term Human Immunodeficiency Virus Infection in Asymptomatic Homosexual and Bisexual Men with Normal CD4+ Lymphocyte Counts: Immunologic and Virologic Characteristics
Alan R. Lifson,Susan Buchbinder,Haynes W. Sheppard,Alison C. Mawle,Judith C. Wilber,Mark Stanley,Clyde E. Hart,Nancy A. Hessol,Scott D. Holmberg +8 more
TL;DR: Compared with men with AIDS, nonprogressors seemed to have a stronger antibody response to six different HIV-related proteins but did not differ significantly in neutralizing antibody or antibody-dependent cellular cytotoxic activity.
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HIV in body fluids during primary HIV infection: implications for pathogenesis, treatment and public health.
Christopher D. Pilcher,Diane C. Shugars,Susan A. Fiscus,William C. Miller,Prema Menezes,Julieta Giner,Beth Dean,Kevin Robertson,Clyde E. Hart,Jeffrey L. Lennox,Joseph J. Eron,Charles B. Hicks +11 more
TL;DR: Peak level HIV replication is established in blood, oropharyngeal tissues and genital tract, but potentially not in CSF, by the time patients are commonly diagnosed with primary HIV infection, and antiretroviral therapy is unlikely to limit initial virus spread to most tissue compartments.
Journal ArticleDOI
The HIV-1 tat protein enhances E2-dependent human papillomavirus 16 transcription
TL;DR: HIV can modulate HPV gene expression in cell culture and that the increased rate of HPV-associated cervical disease in asymptomatic HIV-seropositive women may result from HPV-HIV molecular interactions.