H
Haynes W. Sheppard
Researcher at California Health and Human Services Agency
Publications - 71
Citations - 7168
Haynes W. Sheppard is an academic researcher from California Health and Human Services Agency. The author has contributed to research in topics: Virus & Acquired immunodeficiency syndrome (AIDS). The author has an hindex of 34, co-authored 71 publications receiving 6912 citations. Previous affiliations of Haynes W. Sheppard include University of California, Davis & Aaron Diamond AIDS Research Center.
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Journal ArticleDOI
Full-Length Human Immunodeficiency Virus Type 1 Genomes from Subtype C-Infected Seroconverters in India, with Evidence of Intersubtype Recombination
Kavita S. Lole,Robert C. Bollinger,Ramesh S. Paranjape,Deepak A. Gadkari,Smita Kulkarni,Nicole G. Novak,Roxann G. Ingersoll,Haynes W. Sheppard,Stuart C. Ray +8 more
TL;DR: Because these clones were obtained from Indian seroconverters, they are likely to facilitate vaccine-related efforts in India by providing potential antigens for vaccine candidates as well as for assays of vaccine responsiveness.
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The role of viral phenotype and CCR-5 gene defects in HIV-1 transmission and disease progression
Nelson L. Michael,G Chang,Leslie G. Louie,John R. Mascola,Dale Dondero,Deborah L. Birx,Haynes W. Sheppard +6 more
TL;DR: The protective effect of Δccr5 against disease progression is lost when the infecting virus uses CXCR-4 as a coreceptor, and a distinct survival advantage was shown for those with NSI virus.
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Human immunodeficiency virus type 1 evolution in vivo tracked by DNA heteroduplex mobility assays.
TL;DR: In this article, DNA heteroduplex mobility and tracking analyses were used to monitor the generation of HIV sequence diversity, to estimate quasispecies complexity, and to assess the turnover of genetic variants to approach an understanding of the relationship between viral quasipecies evolution in vivo and disease progression.
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The Role of CCR5 and CCR2 Polymorphisms in HIV-1 Transmission and Disease Progression
Nelson L. Michael,Leslie G. Louie,Amy L. Rohrbaugh,Kathleen A. Schultz,Debora E. Dayhoff,Carol E. Wang,Haynes W. Sheppard +6 more
TL;DR: Although subjects with CCR5 ?
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The characterization of non-progressors: long-term HIV-1 infection with stable CD4+ T-cell levels.
TL;DR: These findings support both a biphasic natural history and the suggestion that the broad range in HIV disease progression rates may be the result of several independent factors interacting in a variety of combinations.