C
Colette Galand
Researcher at University of Paris
Publications - 4
Citations - 105
Colette Galand is an academic researcher from University of Paris. The author has contributed to research in topics: Phosphoglycerate kinase & Hemolytic anemia. The author has an hindex of 4, co-authored 4 publications receiving 103 citations. Previous affiliations of Colette Galand include French Institute of Health and Medical Research.
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Journal ArticleDOI
Acquired erythroenzymopathies in blood disorders: study of 200 cases.
TL;DR: Enzyme abnormalities are frequently found in the red cells of patients with various acquired blood disorders and changes in enzyme activity are usually characterized by the coexistence of deficiency of some enzymes and an increased activity of others.
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Molecular mechanism of erythrocyte pyruvate kinase deficiency
Axel Kahn,Axel Kahn,Joelle Marie,Joelle Marie,Colette Galand,Colette Galand,Pierre Boivin,Pierre Boivin +7 more
TL;DR: The heterogeneity of the molecular mechanisms of the deficiency on the one hand, and the abnormalities of electrofocusing patterns on the other hand seem to indicate that erythrocyte PK deficiency is due to the synthesis by muted structural genes of various abnormal PK molecules.
Journal ArticleDOI
Human erythrocyte phosphoglycerate kinase deficiency: presence in a deficient patient of a stable variant with lowered catalytic activity.
TL;DR: The phosphoglycerate kinase deficiency found in one boy with hemolytic anemia was associated with an almost normal concentration of phosphoglycershire kinase-immunologically related material in the patient's erythrocytes, and the catalytic activity of the mutant enzyme was drastically lowered.
Journal ArticleDOI
Isoelectric focusing of spectrin components in hereditary spherocytosis.
Pierre Boivdm,Colette Galand +1 more
TL;DR: Spectrin purified from erythrocytes of five patients with hereditary spherocytosis gave similar isoelectric focusing patterns, with the exception of the lack of the pH 8.7-focused component in two related patients.