Cornelius Faber

TL;DR: Alginate-based ACH represent a promising strategy to induce directed nerve regrowth following spinal cord injury and adult neural progenitor cells (NPC), which have been shown to promote cell-contact-mediated axon regeneration, can be seeded into alginates as a prerequisite to further improve the regenerative capacity of these artificial growth supportive matrices.

TL;DR: The results show that the syringeal skeleton is optimized for low weight driven by physiological constraints on song production, and a cartilaginous structure suited to play a crucial role in the uncoupling of sound frequency and amplitude control, which permits a novel explanation of the evolutionary success of songbirds.

TL;DR: It is shown that, whereas chemokines are required for leukocyte migration into the CNS, additional MMP-2/9 activities specifically at the border of the CNS parenchyma strongly enhance this transmigration process.

TL;DR: NMR spectroscopy indicated that the aminoglycosides neomycin B and ribostamycin bind to TAR and that neomyin is able to inhibit Tat binding to T AR, and a model structure of the TAR-neomycin complex was calculated, which shows Neomycin reduces the volume of the major groove in which Tat is bound and thus impedes essential protein-RNA contacts.

TL;DR: Results show that high-field MRI allows tracking of a minimal number of cells in vivo, well below the number used in previous studies, opening the possibility of gaining new insights into cell migration and differentiation.