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Costas C. Papagiannitsis
Researcher at Charles University in Prague
Publications - 80
Citations - 2128
Costas C. Papagiannitsis is an academic researcher from Charles University in Prague. The author has contributed to research in topics: Plasmid & Klebsiella pneumoniae. The author has an hindex of 23, co-authored 75 publications receiving 1739 citations. Previous affiliations of Costas C. Papagiannitsis include Pasteur Institute & National and Kapodistrian University of Athens.
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Journal ArticleDOI
Detection of carbapenemases in Enterobacteriaceae: a challenge for diagnostic microbiological laboratories
TL;DR: In this review, screening methods for suspected isolates, direct assays for confirmation of carbapenemase activity, inhibitor-based methods for carbapanemase classification, and molecular-genetic techniques for precise identification of carb APE genes are summarized and proposed.
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An update of the evolving epidemic of blaKPC-2-carrying Klebsiella pneumoniae in Greece (2009–10)
Panagiota Giakkoupi,Costas C. Papagiannitsis,Vivi Miriagou,Olga Pappa,Michalis Polemis,Kyriaki Tryfinopoulou,Leonidas S. Tzouvelekis,Alkiviadis Vatopoulos +7 more
TL;DR: Apart from the epidemic of K PC-2-producing K. pneumoniae belonging to ST258 in Greece, diffusion of bla(KPC-2) to at least 10 additional STs has taken place and co-production of VIM enzymes was observed in isolates of ST147, ST323 and ST383.
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Plasmid-mediated resistance is going wild.
TL;DR: Reports of plasmid-mediated resistance to critically important antimicrobial classes such as broad-spectrum beta-lactams and colistin in Enterobacteriaceae isolates from samples of wildlife origin are focused on.
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An Ertapenem-Resistant Extended-Spectrum-β-Lactamase-Producing Klebsiella pneumoniae Clone Carries a Novel OmpK36 Porin Variant
Aurora García-Fernández,Vivi Miriagou,Costas C. Papagiannitsis,Alessandra Giordano,Mario Venditti,Carlo Mancini,Alessandra Carattoli +6 more
TL;DR: Screening for the ompK36V gene of unrelated K. pneumoniae isolates derived from patients from 2006 to 2009 demonstrated the high frequency of this gene variant as well as its association with ertapenem resistance, reduced susceptibility to meropenem, and susceptibility to imipenem.
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Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Meropenem Hydrolysis Assay with NH4HCO3, a Reliable Tool for Direct Detection of Carbapenemase Activity
Costas C. Papagiannitsis,Vendula Studentova,Radosław Izdebski,Olga Oikonomou,Yvonne Pfeifer,Efthimia Petinaki,Jaroslav Hrabak +6 more
TL;DR: A comparison of a matrix-assisted laser desorption ionization–time of flight mass spectrometric (MALDI-TOF MS) meropenem hydrolysis assay with the Carba NP test showed that both methods exhibited low sensitivity, mainly due to the false-negative results obtained with OXA-48-type producers.