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Jaroslav Hrabak

Researcher at Charles University in Prague

Publications -  99
Citations -  2832

Jaroslav Hrabak is an academic researcher from Charles University in Prague. The author has contributed to research in topics: Plasmid & Klebsiella pneumoniae. The author has an hindex of 21, co-authored 86 publications receiving 2219 citations. Previous affiliations of Jaroslav Hrabak include University of Veterinary and Pharmaceutical Sciences Brno.

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Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study.

Hajo Grundmann, +94 more
TL;DR: The development of a consistent sampling framework and the results of the first structured survey on the occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in European hospitals are reported.
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Carbapenemase Activity Detection by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry

TL;DR: The ability of this method to routinely detect carbapenemases in Enterobacteriaceae and Pseudomonas spp.
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Matrix-Assisted Laser Desorption Ionization–Time of Flight (MALDI-TOF) Mass Spectrometry for Detection of Antibiotic Resistance Mechanisms: from Research to Routine Diagnosis

TL;DR: The results of the presented studies demonstrate that MALDI-TOF MS is a relevant tool for the detection of antibiotic resistance and opens new avenues for both clinical and experimental microbiology.
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Detection of carbapenemases in Enterobacteriaceae: a challenge for diagnostic microbiological laboratories

TL;DR: In this review, screening methods for suspected isolates, direct assays for confirmation of carbapenemase activity, inhibitor-based methods for carbapanemase classification, and molecular-genetic techniques for precise identification of carb APE genes are summarized and proposed.
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Detection of NDM-1, VIM-1, KPC, OXA-48, and OXA-162 Carbapenemases by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry

TL;DR: This work describes a modification of a previously reported MALDI-TOF MS meropenem hydrolysis assay that was validated on 108 carbapenemase-producing members of the Enterobacteriaceae, two NDM-1-producing Acinetobacter baumannii isolates, and 35 carbAPenem-resistant enterobacteria producing no carbapanemase.