Showing papers by "Craig F. Donatucci published in 1993"
TL;DR: The results suggest that both the cholinergic and NANC neuroeffectors and the sinusoidal endothelium are involved in erection and imply that the neuronal nitric oxide/cyclic GMP system is the most likely pathway for penile smooth muscle relaxation and erection.
130 citations
TL;DR: Retrograde and antegrade dissections from the penile hilum to the prostatic area and the glans penis were performed to improve the ability to preserve erectile function during pelvic, urethral, and penile surgery.
82 citations
Journal Article•
TL;DR: A retrospective review of 100 impotent men under age 40 to determine the underlying etiologic factors in the group and to evaluate the role of surgery in their care found that trauma and substance abuse were most common and contributed to the preponderance of vasculogenic impotence.
Abstract: We undertook a retrospective review of 100 impotent men under age 40 to determine the underlying etiologic factors in the group and to evaluate the role of surgery in their care. Although patients ranged in age from 18 to 40 (mean--32.2 years), the number of patients increased steadily with advancing years. The majority of patients (72) had vasculogenic impotence (arteriogenic--15, venogenic--46, mixed--11), followed by psychogenic (13), neurogenic (12) and other causes (4). The differential diagnosis did not correlate with age. Contributing factors were present in 76%, trauma and substance abuse being most common. Essentially equal numbers of patients were treated surgically (40) and with intracavernous injection of vasoactive agents (39). Considerably fewer had a vacuum constriction device (5), oral medication (5), psychotherapy (4), other therapy (4), and none (3). The majority of patients referred to our tertiary urologic practice for treatment of vasculogenic impotence were sent by other urologists. Although the referral source did not appear to influence the choice of treatment, it probably has accounted for the preponderance of vasculogenic impotence in this series.
50 citations
TL;DR: A retrospective analysis of 101 impotent patients using intracavernous self-injections as primary therapy for vasculogenic impotence described the procedure to establish the dosage for home use and the implications of the low dosages relative to previous reports.
49 citations
TL;DR: The effects of prostaglandin E1 appear to be receptor-dependent and prostaglanders E1 monotherapy for impotence could be limited to 20 micrograms.
28 citations
TL;DR: Topical lidocaine is a safe, inexpensive and effective mode of anesthesia for bladder mappings and cold-cup biopsies of small bladder lesions, however, it may be inadequate for lesions large enough to require resection rather than cold- cup biopsy and those at poorly accessible regions of the bladder.
23 citations