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Showing papers in "The Journal of Urology in 1993"


Journal ArticleDOI
TL;DR: From these analyses probability plots and nomograms have been constructed to assist urologists in the preoperative prediction of final pathological stage for patients with clinically localized prostate cancer.

1,232 citations


Journal ArticleDOI
TL;DR: Prostatic intraepithelial neoplasia and histological cancers are surprisingly common in young male patients of both races, and appears to present several decades earlier than clinically detected carcinoma.

762 citations


Journal ArticleDOI
TL;DR: The specific urinary symptoms of nocturia, weak stream, restarting, urgency and sensation of incomplete emptying are strongly age-related and, therefore, may be predictive of a prostatic disease process.

700 citations


Journal ArticleDOI
TL;DR: The combination of assays measuring total PSA immunoreactivity, the noncomplexed molecular form and PSA in complex with alpha 1-antichymotrypsin may facilitate discrimination between prostate cancer and BPH.

683 citations


Journal ArticleDOI
TL;DR: In this article, a laparoscopic dismembered pyeloplasty was performed on 5 patients with ureteropelvic junction obstruction, with operating time ranging from 3 to 7 hours and hospital stay averaged 3 days and all patients returned to normal activity within 1 week.

598 citations



Journal ArticleDOI
TL;DR: In women the abdominal pressure required to cause stress incontinence was unrelated to maximum urethral pressure, and in children with myelodysplasia the values were quite different, indicating that as far as the urethra is concerned abdominal pressure and detrusor pressure are not equivalent forces.

482 citations


Journal ArticleDOI
TL;DR: Patients with tuberous sclerosis and angiomyolipomas were distinctly different from patients with angiomeolipoma only, since they tended to present at a younger age, had a higher incidence of bilateral renal involvement, were more symptomatic, had larger tumors that were more likely to grow, and frequently required surgery.

425 citations


Journal ArticleDOI
TL;DR: At baseline, symptom severity was not correlated with uroflowmetry, post-void residual, prostate size and degree of bladder trabeculation, but was much more strongly related to overall health status than the other measures.

381 citations


Journal ArticleDOI
TL;DR: The efficacy of potassium citrate in preventing new stone formation in idiopathic hypocitraturic calcium nephrolithiasis was shown, and a significant increase in urinary citrate, pH and potassium was caused, whereas placebo did not.

356 citations


Journal ArticleDOI
TL;DR: The influence of age, parity, duration of previous oral contraceptive use, hysterectomy and menopause on the prevalence of urinary incontinence was evaluated by means of a postal questionnaire in women 46 to 86 years old who resided in the city of Göteborg, Sweden.

Journal ArticleDOI
TL;DR: Anatomical radical retropubic prostatectomy can be performed with favorable results in preserving potency and urinary continence in men with clinical stage A or B prostate cancer and better results are achieved in younger men with organ confined cancer.

Journal ArticleDOI
TL;DR: After a mean followup of 2 years it became evident that the recurrence rate after a single epirubicin instillation was decreased by nearly half with the same trend being found in all subgroups examined.

Journal ArticleDOI
TL;DR: The results suggest that a trial of flutamide withdrawal is justified in an asymptomatic patient with an increasing PSA before treatment with more toxic therapies, and shows the importance of documenting sequential elevations in the marker before enrolling a patient in a clinical trial.

Journal ArticleDOI
TL;DR: There was an apparent plateau in the frequency and urgency among patients after approximately 5 years with symptoms and more than 60% of the patients were unable to enjoy usual activities or were excessively fatigued and 53.7% reported depression.

Journal ArticleDOI
TL;DR: The status of capsular margins should not influence the decision on whether to administer immediate postoperative adjuvant therapy following radical prostatectomy, and tumors with capsular penetration should be stratified into groups having similar risks of progression according to the extent of Capsular penetration, surgical margins of resection and grade.

Journal ArticleDOI
TL;DR: This study demonstrates that measurement of tumor volume in radical prostatectomy specimens need not be performed as part of the routine pathological analysis of radical prostateCTomy specimens, since it does not provide additional information beyond that of Gleason score and the status of capsular margins.

Journal ArticleDOI
TL;DR: The identification of a predominant alpha 1-AR mRNA in human prostate identifies a potential need for subtype selective pharmaceutical agents that could be very important clinically in the treatment of diseases such as BPH.

Journal ArticleDOI
TL;DR: With excellent disease-specific survival and recurrence rates comparable to that achieved with radical nephrectomy, nephron-sparing surgery can be confidently utilized in treating patients with stage T1 RCC lesions and a normal contralateral kidney.


Journal ArticleDOI
TL;DR: A bipartite myogenic mechanism is proposed to account for the involuntary contractions yet allow neurally triggered unitary voiding contractions in the overactive detrusor.

Journal ArticleDOI
TL;DR: It is proposed that the dense band pattern represents the structural norm of agingdetrusor, heralds a process of muscle cell de-differentiation in the detrusor accompanying natural aging, and may affect exchange and storage of ions involved in the excitation-contraction coupling mechanism of muscle cells through depletion of caveolae.

Journal ArticleDOI
TL;DR: Preliminary studies indicate that autologous cartilage-polymer gel solutions may be potentially useful in the endoscopic treatment of reflux.

Journal ArticleDOI
TL;DR: Overall success rate has been 86% with little difference being detected between the success that is obtained with primary and secondary obstructions (85% versus 86%).

Journal ArticleDOI
TL;DR: Feelings of feasibility of using polyglycolic acid polymers as substrates for the creation of human urothelial and muscle grafts for genitourinary reconstruction are suggested.

Journal ArticleDOI
TL;DR: This retrospective analysis further substantiates the philosophy that single stage pelvic lymphadenectomy with en bloc radical cystectomy can provide long-term progression-free survival, particularly for patients with localized primary tumors and minimal metastatic nodal disease.

Journal ArticleDOI
TL;DR: Results with primary retroperitoneal lymphadenectomy in 464 patients with clinical stage A nonseminomatous germ cell testis cancer (1965 to 1989) were reviewed and were directly comparable with series using radiotherapy or surveillance.

Journal ArticleDOI
TL;DR: Pre-transplant nephrectomy was done in a 25-year-old man for calculous pyelonephritis using a retroperitoneal laparoscopic approach with a newly devised ligature applicator-dissector- kidney retractor.

Journal ArticleDOI
TL;DR: The results demonstrate the requirement for T lymphocytes in BCG-mediated antitumor activity and further demonstrate that the presence of both CD4 and CD8 subsets are required and suggest that it is a localized phenomenon that does not induce protective immunity.

Journal ArticleDOI
Stefano Palea1, Walter Artibani1, E. Ostardo1, D.G. Trist1, C. Pietra1 
TL;DR: Results are consistent with the presence of a purinergic neurotransmission in parasympathetic nerve terminals of the urinary bladder affected by IC, probably as a consequence of alterations in the innervation and/or electrical coupling between smooth muscle cells.