The development of polymeric luminescent nanomaterials for biomedical applications has recently attracted a large amount of attention due to the remarkable advantages of these materials compared with small organic dyes and fluorescent inorganic nanomaterials. Among these polymeric luminescent nanomaterials, polymeric luminescent nanomaterials based on dyes with aggregation-induced emission (AIE) properties should be of great research interest due to their unique AIE properties, the designability of polymers and their multifunctional potential. In this review, the recent advances in the design and biomedical applications of polymeric luminescent nanomaterials based on AIE dyes is summarized. Various design strategies for incorporation of these AIE dyes into polymeric systems are included. The potential biomedical applications such as biological imaging, and use in biological sensors and theranostic systems of these polymeric AIE-based nanomaterials have also been highlighted. We trust this review will attract significant interest from scientists from different research fields in chemistry, materials, biology and interdisciplinary areas.

Polymeric AIE-based nanoprobes for biomedical applications: recent advances and perspectives.

Preparation of amine functionalized carbon nanotubes via a bioinspired strategy and their application in Cu2+ removal

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Facile synthesis of polymeric fluorescent organic nanoparticles based on the self-polymerization of dopamine for biological imaging

A facile one-pot Mannich reaction for the construction of fluorescent polymeric nanoparticles with aggregation-induced emission feature and their biological imaging

Microwave-assisted multicomponent reactions for rapid synthesis of AIE-active fluorescent polymeric nanoparticles by post-polymerization method.

The interaction of manufactured nanomaterials with environmental and biological systems has been a subject of great research interest for a long time. In the present study, adsorption of a universal environmental organic material (named tannic acid (TA)) on carbon nanotubes (CNTs) was investigated. The influence of CNT properties and pH values on the sorption capacity of CNTs for TA was also evaluated. Our results demonstrated that the sorption capacity of CNTs was positively correlated with their specific surface areas. Furthermore, TA could effectively enhance the water dispersibility of CNTs and reduce their cytotoxicity. Our results implied that TA could influence the environmental behavior and biological responses of the manufactured nanomaterials, reminding us that much more attention should be paid to the synergistic toxicity of nanomaterials when we evaluate their environmental impacts.

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Cuiying Zhou

Papers

Interaction of tannic acid with carbon nanotubes: enhancement of dispersibility and biocompatibility