D
D. A. Smagin
Researcher at Russian Academy of Sciences
Publications - 46
Citations - 461
D. A. Smagin is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: Social defeat & Ventral tegmental area. The author has an hindex of 11, co-authored 40 publications receiving 328 citations.
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Journal ArticleDOI
Repeated positive fighting experience in male inbred mice
TL;DR: The sensory contact model (SCM) is applied to study repeated aggression in mice and develops pronounced aggressiveness, anxiety and impulsivity, disturbances in motivated and cognitive behaviors, and impairments of sociability.
Journal ArticleDOI
Dysfunction in Ribosomal Gene Expression in the Hypothalamus and Hippocampus following Chronic Social Defeat Stress in Male Mice as Revealed by RNA-Seq.
D. A. Smagin,Irina L. Kovalenko,A.G. Galyamina,A. O. Bragin,Yuriy L. Orlov,Natalia N. Kudryavtseva +5 more
TL;DR: The influence of 21-day period of social stress on ribosomal gene expression in five brain regions was studied using the RNA-Seq database to identify a pharmacological treatment of ribosome biogenesis abnormalities in the brain of patients with “ribosomopathies.”
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Altered Slc25 family gene expression as markers of mitochondrial dysfunction in brain regions under experimental mixed anxiety/depression-like disorder.
TL;DR: Altered expression of the Slc25* genes may serve as a marker of mitochondrial dysfunction in brain, which accompanies the development of many neurological and psychoemotional disorders.
Journal ArticleDOI
[Serotonergic genes in the development of anxiety/depression-like state and pathology of aggressive behavior in male mice: RNA-seq data].
Natalia N. Kudryavtseva,D. A. Smagin,Irina L. Kovalenko,A.G. Galyamina,Galina B. Vishnivetskaya,Vladimir N. Babenko,Yu. L. Orlov +6 more
TL;DR: The complex pattern of differential expression of serotonergic genes in brain regions developing under repeated agonistic interactions in mice in dependence on behavioral pathology have been observed.
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Interaction of Depression and Anxiety in the Development of Mixed Anxiety/Depression Disorder. Experimental Studies of the Mechanisms of Comorbidity (review)
TL;DR: This review of the literature and the own data analyzes the relationship between anxiety and depression and concludes that existing antidepressants and anxiolytics exert their therapeutic effects even in the monopolar development of anxiety or depression in only a limited number of cases.