D.F. Cole

TL;DR: The object of the present paper is to review and discuss with respect to aqueous humour secretion the role of ciliary epithelial transport; the ultrastructural basis of the transport system and the possible role of ultrafiltration; and the mode of action of the carbonic anhydrase inhibitor, acetazolamide.

TL;DR: The location of adenosine triphosphatase (ATPase) in the ciliary epithelium has been investigated on fresh-frozen sections mounted on cover-slips and it is pointed out that the distribution of ouabain-sensitive ATPase may be related to that of succinic dehydrogenase activity.

TL;DR: All procedures converge in indicating that active transport of chloride can occur across the ciliary epithelium in the direction stroma→posterior chamber and equations derived from considerations of irreversible thermodynamics were used to obtain estimates of the relative contributions of Na+ and Cl− ions to the total short-circuit current.

TL;DR: The effects of some pharmacological substances on active transport across the ciliary epithelium are described to relate this action to the physiological control of intraocular pressure (IOP) and to the known in vitro actions of certain drugs.

TL;DR: It is suggested that noradrenaline in the anterior chamber may be taken up in storage sites in the iris, thus diminishing the amount reaching the vascular smooth muscle, and that these sites are blocked by cocaine.