D
D. Glenn Kennedy
Researcher at Department of Agriculture and Rural Development
Publications - 49
Citations - 1747
D. Glenn Kennedy is an academic researcher from Department of Agriculture and Rural Development. The author has contributed to research in topics: Mass spectrometry & Veterinary drug. The author has an hindex of 26, co-authored 48 publications receiving 1646 citations. Previous affiliations of D. Glenn Kennedy include Central Science Laboratory.
Papers
More filters
Journal ArticleDOI
Determination of furazolidone in porcine tissue using thermospray liquid chromatography–mass spectrometry and a study of the pharmacokinetics and stability of its residues
TL;DR: The assay is used to investigate the depletion of furazolidone from tissue and sample stability post mortem and it is necessary to snap-freeze samples by immersion in liquid nitrogen immediately upon collection in order to improve the stability of residues in tissue.
Journal ArticleDOI
Confirmatory assay for the determination of tetracycline, oxytetracycline, chlortetracycline and its isomers in muscle and kidney using liquid chromatography-mass spectrometry.
TL;DR: The formation of epimers and tautomers of the tetracyclines, their presence in incurred tissues and difficulties in their accurate quantitation is discussed.
Journal ArticleDOI
Enzyme immunoassay for semicarbazide--the nitrofuran metabolite and food contaminant.
TL;DR: A novel carboxyphenyl SEM derivative was used to raise a polyclonal antibody that has been incorporated into a semi-quantitative microtitre plate ELISA, validated according to the criteria set out in Commission Decision 2002/657/EC, for use with chicken muscle.
Journal ArticleDOI
Monoclonal antibody-based ELISA for the quantification of nitrofuran metabolite 3-amino-2-oxazolidinone in tissues using a simplified sample preparation
TL;DR: A sensitive and specific monoclonal ELISA for the determination of tissue bound furazolidone metabolite 3-amino-2-oxazolidinone (AOZ) is described, which approaches the established confirmatory LC–MS/MS able to quantify tissue-bound AOZ at levels as low as 0.3 μg kg −1.
Journal ArticleDOI
Production and characterisation of polyclonal antibodies to a derivative of 3-amino-2-oxazolidinone, a metabolite of the nitrofuran furazolidone
TL;DR: In this paper, polyclonal antibodies were produced to detect 3-amino-2-oxazolidinone (AOZ), a stable metabolite of the nitrofuran antibiotic furazolidone, following derivatisation with o-nitrobenzaldehyde.