D
D. Levinson
Publications - 2
Citations - 2749
D. Levinson is an academic researcher. The author has contributed to research in topics: Fusion protein & Binding site. The author has an hindex of 2, co-authored 2 publications receiving 2711 citations.
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Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli.
James S. Huston,D. Levinson,Meredith Mudgett-Hunter,M S Tai,Jirí Novotný,Michael N. Margolies,R J Ridge,Robert E. Bruccoleri,Edgar Haber,R Crea +9 more
TL;DR: A biosynthetic antibody binding site, which incorporated the variable domains of anti-digoxin monoclonal antibody 26-10 in a single polypeptide chain, was produced in Escherichia coli by protein engineering.
Journal ArticleDOI
A bifunctional fusion protein containing Fc-binding fragment B of staphylococcal protein A amino terminal to antidigoxin single-chain Fv.
TL;DR: Analysis of the expressed fusion protein suggests that the FB-sFv holds promise for the development of multifunctional, targetable single-chain proteins.