D
D. S. Knopman
Researcher at Mayo Clinic
Publications - 78
Citations - 15872
D. S. Knopman is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Dementia & Frontotemporal dementia. The author has an hindex of 46, co-authored 78 publications receiving 13867 citations. Previous affiliations of D. S. Knopman include Mario Negri Institute for Pharmacological Research.
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Journal ArticleDOI
Classification of primary progressive aphasia and its variants
Maria Luisa Gorno-Tempini,Maria Luisa Gorno-Tempini,Argye E. Hillis,Sandra Weintraub,Andrew Kertesz,Mario F. Mendez,Stefano F. Cappa,J. M. Ogar,Jonathan D. Rohrer,Sandra E. Black,Bradley F. Boeve,Facundo Manes,Nina F. Dronkers,Rik Vandenberghe,Katya Rascovsky,Karalyn Patterson,Bruce L. Miller,D. S. Knopman,John R. Hodges,M.-Marsel Mesulam,Murray Grossman +20 more
TL;DR: This article provides a classification of primary progressive aphasia (PPA) and its 3 main variants to improve the uniformity of case reporting and the reliability of research results.
Journal ArticleDOI
Cardiovascular risk factors and cognitive decline in middle-aged adults
D. S. Knopman,Lori L. Boland,Thomas H. Mosley,George Howard,Duanping Liao,Moyses Szklo,Paul G. McGovern,Aaron R. Folsom +7 more
TL;DR: Hypertension and diabetes mellitus were positively associated with cognitive decline over 6 years in this late middle-aged population and interventions aimed at hypertension or diabetes that begin before age 60 might lessen the burden of cognitive impairment in later life.
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Comparison of Different MRI Brain Atrophy Rate Measures with Clinical Disease Progression in AD
C. R. Jack,Maria Shiung,Jeffrey L. Gunter,P. C. O'Brien,Stephen D. Weigand,D. S. Knopman,B. F. Boeve,Robert J. Ivnik,Glenn E. Smith,Ruth H. Cha,Eric G. Tangalos,R. C. Petersen +11 more
TL;DR: These data support the use of rates of change from serial MRI studies in addition to standard clinical/psychometric measures as surrogate markers of disease progression in AD, and atrophy on MRI was detected more consistently than decline on specific cognitive tests/rating scales.
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Prevalence of mild cognitive impairment is higher in men. The Mayo Clinic Study of Aging.
R. C. Petersen,Rosebud O. Roberts,D. S. Knopman,Yonas E. Geda,Ruth H. Cha,Vernon S. Pankratz,B. F. Boeve,Eric G. Tangalos,Robert J. Ivnik,Walter A. Rocca +9 more
TL;DR: The study suggests that approximately 16% of elderly subjects free of dementia are affected by MCI, and amnestic MCI is the most common type.
Journal ArticleDOI
Cognitive impairment in hemodialysis patients is common.
Anne M. Murray,David E. Tupper,David E. Tupper,D. S. Knopman,D. T. Gilbertson,S. L. Pederson,S. Li,Glenn E. Smith,Angela Hochhalter,Allan J. Collins,Robert L. Kane +10 more
TL;DR: Cognitive testing in hemodialysis patients before dialysis initiation and periodically may be warranted and further studies are needed to determine whether dialysis exacerbates the cognitive impairment attributable to underlying disease.