D
D.W. Burton
Researcher at United States Department of Veterans Affairs
Publications - 2
Citations - 224
D.W. Burton is an academic researcher from United States Department of Veterans Affairs. The author has contributed to research in topics: Alkaline phosphatase & Osteoblast. The author has an hindex of 2, co-authored 2 publications receiving 222 citations.
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1,25-Dihydroxyvitamin D3 stimulates the alkaline phosphatase activity of osteoblast-like cells.
TL;DR: It is speculated that the stimulatory effect of 1,25(OH)2D3 on the alkaline phosphatase activity of osteoblast-like cells indicates a direct involvement of 1%, 25-dihydroxyvitamin D3 and other vitamin D3 metabolites in bone mineralization.
Journal ArticleDOI
Mechanism of action of 1,25-dihydroxyvitamin D3-induced stimulation of alkaline phosphatase in cultured osteoblast-like cells.
TL;DR: It is suggested that 1,25(OH)2D3-induced stimulation of alkaline phosphatase in the osteoblast-like cells involves genome activation and de novo protein synthesis.