The present study aimed at synthesising chitosan bound ginger nanocarriers for slow and controlled release of the drug 5-amino salicylic acid (5-ASA) against inflammatory bowel diseases (IBD). The chitosan, extracted from naturally occurring biopolymer chitin, was reacted to ginger extract (Zingiber officinale) to prepare chitosan-bounded ginger derived nanocarriers (C-GDNC) and further loaded with 5-ASA drug. The as-obtained drug loaded chitosan coated ginger derived nanocarriers (D-C-GNDC) were studied for controlled release of 5-ASA. In vitro experimental data implied slow and controlled release of 5-ASA and were kinetically justified by applying different kinetic models. The obtained percent drug loading capacity and entrapment efficiency were more than 50%. Various experimental factors affecting swelling controlled drug release of 5-ASA, such as change in pH of release medium, chemical composition of nanocarriers, percent drug loading, and simulated biofluids as release media, were investigated. The prepared nanomaterials were well characterized and examined for chemical stability and in vitro cytotoxicity to check their biocompatible nature. The overall studies concluded that the controlled release of 5-ASA was favourable at the gastrointestinal pH which is desirably beneficial against inflammation of bowl.

Functionalization of ginger derived nanoparticles with chitosan to design drug delivery system for controlled release of 5-amino salicylic acid (5-ASA) in treatment of inflammatory bowel diseases: An in vitro study

Perspectives on composite films of chitosan-based natural products (Ginger, Curcumin, and Cinnamon) as biomaterials for wound dressing

As is already known, solar photovoltaic (PV) technology is a widely accepted technology for power generation worldwide. However, it is scientifically proven that its power output decreases with an increase in the temperature of the PV module. Such an important issue is controlled by adopting a number of cooling mechanisms for the PV module. The present experimental study assesses the effect of a fanless CPU heat pipe on the performance of a PV module. The experiment was conducted in June in real weather conditions in Yekaterinburg, Russian Federation. The comparative analysis of two PV panels (i.e., cooled, and uncooled) based on the electrical energy, exergy performance, economic, embodied energy and energy payback (5E) for the two systems is presented and discussed. The key results from the study are that the average temperature reduction from the cooling process is 6.72 °C. The average power for the cooled panel is 11.39 W against 9.73 W for the uncooled PV panel; this represents an increase of 1.66 W for the cooled module. Moreover, the average improvements in the electrical efficiency, and embodied energy recorded for a cooled PV panel 2.98%, and 438.52 kWh, respectively. Furthermore, the calculations of the levelized cost of energy (LCE) for the cooled PV panel indicate that it can range from 0.277–0.964 USD/kWh, while that for the uncooled PV panel also ranges from 0.205–0.698 USD/kWh based on the number of days of operation of the plant.

/pdf/experimental-study-on-performance-enhancement-of-a-3rb0vnzz.pdf

Experimental Study on Performance Enhancement of a Photovoltaic Module Incorporated with CPU Heat Pipe—A 5E Analysis

Dabing Luo

Papers

Solar energy harvesting technologies for PV self-powered applications: A comprehensive review

A Hybrid Self-Powered System Based on Wind Energy Harvesting for Low-Power Sensors on Canyon Bridges

Vibration energy harvesting system based on track energy-recycling technology for heavy-duty freight railroads

A U-shaped kinetic energy harvester for application in a near-zero energy parking system

A vibration energy harvesting system for Self-Powered applications in heavy railways