D
Dada Patil
Researcher at Serum Institute of India (India)
Publications - 19
Citations - 431
Dada Patil is an academic researcher from Serum Institute of India (India). The author has contributed to research in topics: Withania somnifera & High-performance liquid chromatography. The author has an hindex of 10, co-authored 18 publications receiving 367 citations. Previous affiliations of Dada Patil include Savitribai Phule Pune University & Symbiosis International University.
Papers
More filters
Journal ArticleDOI
Immunomodulatory activity of Asparagus racemosus on systemic Th1/Th2 immunity: Implications for immunoadjuvant potential
Manish Gautam,Santanu Saha,Sarang Bani,Anpurna Kaul,Sanjay Mishra,Dada Patil,Naresh Kumar Satti,K. A. Suri,Sunil Gairola,K. Suresh,Suresh Jadhav,Gulam Nabi Qazi,Bhushan Patwardhan +12 more
TL;DR: Mixed Th1/Th2 activity of ARE supports its immunoadjuvant potential, and treatment with ARE resulted in significant increase of CD3(+) and CD4/CD8(+) percentages suggesting its effect on T cell activation.
Journal ArticleDOI
Determination of withaferin A and withanolide A in mice plasma using high-performance liquid chromatography-tandem mass spectrometry: application to pharmacokinetics after oral administration of Withania somnifera aqueous extract.
Dada Patil,Manish Gautam,Sanjay Mishra,Suresh Karupothula,Sunil Gairola,Suresh Jadhav,Shrikrishna Pawar,Bhushan Patwardhan +7 more
TL;DR: A new, selective and rapid high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method has been developed and validated for simultaneous determination of WA and WLD in mice plasma and revealed that withaferin A has one and half times more relative bioavailability as compared to withanolide A.
Journal ArticleDOI
Development and biological evaluation of Gymnema sylvestre extract-loaded nonionic surfactant-based niosomes
Bhagyashree Kamble,Seema Talreja,Ankur Gupta,Dada Patil,Deepa Pathak,Ismail Moothedath,B. Duraiswamy +6 more
TL;DR: The niosome formulation demonstrated significant blood glucose level reduction in an oral glucose tolerance test, and increased antihyperglycemic activity compared with the parent extract in an alloxan-induced diabetic model, justifying the potential of niosomes for improving the efficacy of G. sylvestre extract as antidiabetic.
Journal ArticleDOI
Physicochemical Stability and Biological Activity of Withania somnifera Extract under Real-Time and Accelerated Storage Conditions
Dada Patil,Manish Gautam,Umesh U. Jadhav,Sanjay Mishra,Suresh Karupothula,Sunil Gairola,Suresh Jadhav,Bhushan Patwardhan +7 more
TL;DR: The results suggest a significant decline in withaferin A and withanolide A content under real and accelerated conditions and may help in proposing suitable guidance for storage conditions and shelf life of ashwagandha formulations.
Journal ArticleDOI
Effect of botanical immunomodulators on human CYP3A4 inhibition: implications for concurrent use as adjuvants in cancer therapy
TL;DR: The findings suggest that constituents of TCE extract especially protoberberine alkaloids have the potential to interact with cancer chemotherapy agents that are metabolized by CYP3A4 in vivo.