D
Dagmar Pfeiffer
Researcher at University of Graz
Publications - 9
Citations - 561
Dagmar Pfeiffer is an academic researcher from University of Graz. The author has contributed to research in topics: Mesenchymal stem cell & P70-S6 Kinase 1. The author has an hindex of 7, co-authored 9 publications receiving 437 citations. Previous affiliations of Dagmar Pfeiffer include Medical University of Graz & Danube University Krems.
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Journal ArticleDOI
Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT-mTOR-S6K signaling and drug responses.
Angelika Riedl,Michaela Schlederer,Karoline Pudelko,Mira Stadler,Stefanie Walter,Daniela Unterleuthner,Christine Unger,Nina Kramer,Markus Hengstschläger,Lukas Kenner,Lukas Kenner,Dagmar Pfeiffer,Georg Krupitza,Helmut Dolznig +13 more
TL;DR: Colon cancer spheroids have decreased AKT–mTOR–S6K activity, spatial differences in signaling intensity as well as differing responses upon inhibition of the AKT-mTOR-S6k or mitogen-activated protein kinase (MAPK) axes in comparison with 2D cultures.
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miR-146a, miR-146b, and miR-155 increase expression of IL-6 and IL-8 and support HSP10 in an In vitro sepsis model.
TL;DR: Evidence is provided for the central role of selected miRNAs in sepsis and their use in the development of small interfering RNA therapeutics to target immune cells and sepsi pathways.
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Comparative study of regenerative effects of mesenchymal stem cells derived from placental amnion, chorion and umbilical cord on dermal wounds.
Juliane Ertl,Melanie Pichlsberger,Alexandru Tuca,Paul Wurzer,Jakob Fuchs,Stefan H. Geyer,Barbara Maurer-Gesek,Wolfgang Weninger,Dagmar Pfeiffer,Vladimir Bubalo,Daryousch Parvizi,Lars P. Kamolz,Ingrid Lang +12 more
TL;DR: All three PMSC types exert similar beneficial effects on wound closure and neovascularization in the authors' mouse model, which warrants further investigation in clinical trials.
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Placental mesenchymal stromal cells derived from blood vessels or avascular tissues: what is the better choice to support endothelial cell function?
Julia König,Gregor Weiss,Daniele Rossi,Karin Wankhammer,Andreas Reinisch,Manuela Kinzer,Berthold Huppertz,Dagmar Pfeiffer,Ornella Parolini,Ingrid Lang +9 more
TL;DR: Bv-MSCs express a very similar surface marker profile compared with av- MSCs and could be differentiated toward the adipogenic and osteogenic lineages, suggesting that they are suitable for cell transplantation settings and might be valuable to stimulate angiogenesis especially in ischemic tissues.
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Endothelialization of electrospun polycaprolactone (PCL) small caliber vascular grafts spun from different polymer blends
Dagmar Pfeiffer,Dagmar Pfeiffer,Christina Stefanitsch,K. Wankhammer,Marc Müller,Lutz Dreyer,Benjamin Krolitzki,Holger Zernetsch,Birgit Glasmacher,C. Lindner,Achim Lass,M. Schwarz,W. Muckenauer,Ingrid Lang +13 more
TL;DR: Compared different compositions of electrospun scaffolds with conventional ePTFE grafts with an inner diameter of 4 mm as well as different pre-coatings to create an optimized physiological interface for endothelialization showed good results, with best results obtained with fibronectin-coated PCL/PLA/PEG grafts.