Daisuke Kinose

TL;DR: GORD symptoms were identified as an important factor associated with COPD exacerbation and were significantly associated with the occurrence of exacerbations.

TL;DR: This is the first longitudinal study to demonstrate that exacerbations are involved in emphysema progression in patients with chronic obstructive pulmonary disease and establish a novel simulation model that found that not only enlargement of preexisting low-attenuation areas but also coalescence of adjoining low-attention areas due to alveolar wall destruction caused emphySEma progression.

TL;DR: It is suggested that COPD itself could be a risk factor for osteoporosis and that chest CT scanning is useful for the management of COPD as a systemic disease.

TL;DR: A low BMI is associated with the presence of emphysema, but not with airway wall thickening, in male smokers who have COPD, which support the concept of different COPD phenotypes and suggest that there may be different systemic manifestations of these phenotypes.

TL;DR: IOS measurements, especially indices of peripheral airway function, are significantly correlated with health status and dyspnea in patients with COPD and may be a useful clinical tool not only for detecting pulmonary functional impairment, but also to some extent at least estimating the patient's quality of daily life and well-being.