D
Daisy Hoagland
Researcher at Wyss Institute for Biologically Inspired Engineering
Publications - 1
Citations - 67
Daisy Hoagland is an academic researcher from Wyss Institute for Biologically Inspired Engineering. The author has contributed to research in topics: Virus & Viral entry. The author has an hindex of 1, co-authored 1 publications receiving 58 citations.
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Human organs-on-chips as tools for repurposing approved drugs as potential influenza and COVID19 therapeutics in viral pandemics
Longlong Si,Haiqing Bai,Melissa Rodas,Wuji Cao,Crystal Oh,Amanda Jiang,Rasmus Møller,Daisy Hoagland,Kohei Oishi,Shu Horiuchi,Skyler Uhl,Daniel Blanco-Melo,Daniel Blanco-Melo,Daniel Blanco-Melo,Randy A. Albrecht,Wen-Chun Liu,Tristan X. Jordan,Benjamin E. Nilsson-Payant,James Logue,Robert Haupt,Marisa McGrath,Stuart Weston,Atiq Nurani,Seong Min Kim,Danni Y. Zhu,Kambez H. Benam,Girija Goyal,Sarah E. Gilpin,Rachelle Prantil-Baun,Rani K. Powers,Kenneth R Carlson,Matthew B. Frieman,Benjamin R. tenOever,Donald E. Ingber,Donald E. Ingber,Donald E. Ingber +35 more
TL;DR: Human organ-on-a-chip (Organ Chip) microfluidic culture devices lined by a highly differentiated, primary, human lung airway epithelium cultured under an air-liquid interface and fed by continuous medium flow can be used to model virus entry, replication, strain-dependent virulence, host cytokine production, and recruitment of circulating immune cells in response to infection by influenza.