Damien J. Ferraro

TL;DR: It is possible to detect seizures automatically in a prolonged EEG recording using computationally efficient unsupervised algorithms, but both the quality of the EEG and the analysis method employed affect PPV and sensitivity.

TL;DR: This article addresses the temporal and anatomical parameters that must be understood in order to address the general question of whether seizures damage the brain during the chronic epilepsy that follows status epilepticus.

TL;DR: Spontaneous epileptic seizures in kainate‐treated rats are used to examine the efficacy of topiramate (TPM) with a repeated‐measures, crossover protocol.

TL;DR: In the PILO model, pre-treatment with CHX does not affect mossy fiber sprouting in the IML of epileptic rats and does not prevent the formation of recurrent excitatory circuits, which suggest that the develoment of spontaneous motor seizures could occur without detectable hippocampal neuron loss or mossy Fiber sprouting.

TL;DR: The use of a three-channel radiotelemetry system to record spontaneous electrographic interictal "spikes" and seizure activity from the cortical surface and the two hippocampi has allowed continuous recording before, during, and several months after kainate-induced status epilepticus.