Phosphinoaryl- and phosphinoalkyloxazolines as new chiral ligands for enantioselective catalysis: Very high enantioselectivity in palladium catalyzed allylic substitutions

Compounds of formula (1) are described and the salts, solvates, hydrates and N-oxides thereof, in which R?1, R2, R3, R4, R5, R6 and R7? have the meanings given in Claim 1. The compounds are selective inhibitors of protein kinases, especially src-family protein kinases and are of use in the prophylaxis and treatment of immune diseases, hyperproliferative disorders and other diseases in which inappropriate protein kinase action is believed to have a role.

Substituted 2-anilinopyrimidines useful as protein kinase inhibitors

Recent developments in methods for the esterification and protection of the carboxyl group

The synthetic utility of oxazolines in aromatic substitution

Knoevenagel condensation catalysed by aluminium oxide.

Oxazolines. XI. Synthesis of functionalized aromatic and aliphatic acids. Useful protecting group for carboxylic acids against Grignard and hydride reagents

Dan Haidukewych

Papers

Oxazolines. XI. Synthesis of functionalized aromatic and aliphatic acids. Useful protecting group for carboxylic acids against Grignard and hydride reagents

Reactions Catalyzed by Potassium Fluoride. V. The Kinetics of the Knoevenagel Reaction