scispace - formally typeset
D

Dan Jin

Researcher at Southern Medical University

Publications -  25
Citations -  543

Dan Jin is an academic researcher from Southern Medical University. The author has contributed to research in topics: Wnt signaling pathway & Cellular differentiation. The author has an hindex of 14, co-authored 23 publications receiving 446 citations.

Papers
More filters
Journal ArticleDOI

The dose-effect of icariin on the proliferation and osteogenic differentiation of human bone mesenchymal stem cells.

TL;DR: It is found that icariin had a dose-dependent effect on the proliferation and osteogenic differentiation of hBMSCs in a suitable concentration range from 10−9 M to 10−6 M, but at concentrations above 10−5 M, the cytotoxicity limited its use.
Journal ArticleDOI

The Potential Use of Allogeneic Platelet-Rich Plasma for Large Bone Defect Treatment: Immunogenicity and Defect Healing Efficacy:

TL;DR: This study has demonstrated the promising use of allogeneic PRP for bone defect treatment with negligible immunogenicity, great healing efficacy, potentially more consistent quality, and no additional health burden to patients; additionally, the synergetic enhancing effect found between allogeneIC PRP and autologous MSCs may shed a light on developing new therapeutic strategies for largeBone defect treatment.
Journal ArticleDOI

The biological effects and mechanisms of calcitonin gene-related peptide on human endothelial cell.

TL;DR: It is concluded that CGRP is a strong proangiogenic growth factor, thereby contributing to bone development and remodeling by promoting angiogenesis.
Journal ArticleDOI

Prognostic Value of Ezrin in Various Cancers: A Systematic Review and Updated Meta-analysis.

TL;DR: A systematic review and meta-analysis suggests that Ezrin may be a potential prognostic marker in cancer patients because high Ezrin is associated with a poor prognosis in a variety of solid tumors.
Journal ArticleDOI

Neuropeptide Y stimulates osteoblastic differentiation and VEGF expression of bone marrow mesenchymal stem cells related to canonical Wnt signaling activating in vitro.

TL;DR: NPY significantly promoted osteoblastic differentiation of BMSCs in a concentration-dependent manner and up-regulated the expression levels of proteins including β- catenin and p-GSK-3β and the mRNA level of β-catenin.