D
Dan Jin
Researcher at Southern Medical University
Publications - 25
Citations - 543
Dan Jin is an academic researcher from Southern Medical University. The author has contributed to research in topics: Wnt signaling pathway & Cellular differentiation. The author has an hindex of 14, co-authored 23 publications receiving 446 citations.
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Journal ArticleDOI
The dose-effect of icariin on the proliferation and osteogenic differentiation of human bone mesenchymal stem cells.
Junjun Fan,Liang-Guo Cao,Tao Wu,De-Xin Wang,Dan Jin,Shan Jiang,Zhi-Yong Zhang,Long Bi,Guo-Xian Pei +8 more
TL;DR: It is found that icariin had a dose-dependent effect on the proliferation and osteogenic differentiation of hBMSCs in a suitable concentration range from 10−9 M to 10−6 M, but at concentrations above 10−5 M, the cytotoxicity limited its use.
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The Potential Use of Allogeneic Platelet-Rich Plasma for Large Bone Defect Treatment: Immunogenicity and Defect Healing Efficacy:
Zhi-Yong Zhang,Ai-wen Huang,Jun Jun Fan,Kuan-hai Wei,Dan Jin,Bin Chen,Dan Li,Long Bi,Jun Wang,Guoxian Pei +9 more
TL;DR: This study has demonstrated the promising use of allogeneic PRP for bone defect treatment with negligible immunogenicity, great healing efficacy, potentially more consistent quality, and no additional health burden to patients; additionally, the synergetic enhancing effect found between allogeneIC PRP and autologous MSCs may shed a light on developing new therapeutic strategies for largeBone defect treatment.
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The biological effects and mechanisms of calcitonin gene-related peptide on human endothelial cell.
Yonghua Tuo,Xiaolei Guo,Xinxin Zhang,Zhao Wang,Jian Zhou,Liheng Xia,Yongtao Zhang,Jun Wen,Dan Jin +8 more
TL;DR: It is concluded that CGRP is a strong proangiogenic growth factor, thereby contributing to bone development and remodeling by promoting angiogenesis.
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Prognostic Value of Ezrin in Various Cancers: A Systematic Review and Updated Meta-analysis.
TL;DR: A systematic review and meta-analysis suggests that Ezrin may be a potential prognostic marker in cancer patients because high Ezrin is associated with a poor prognosis in a variety of solid tumors.
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Neuropeptide Y stimulates osteoblastic differentiation and VEGF expression of bone marrow mesenchymal stem cells related to canonical Wnt signaling activating in vitro.
TL;DR: NPY significantly promoted osteoblastic differentiation of BMSCs in a concentration-dependent manner and up-regulated the expression levels of proteins including β- catenin and p-GSK-3β and the mRNA level of β-catenin.