Studying non-covalent drug-DNA interactions.

Interactions of hemin with bovine serum albumin and human hemoglobin: A fluorescence quenching study

Study of the binding interactions between uric acid and bovine serum albumin using multiple spectroscopic techniques

Melamine, beyond the kidney: A ubiquitous endocrine disruptor and neurotoxicant?

Investigation of the binding affinity in vitamin B12-Bovine serum albumin system using various spectroscopic methods.

Spectroscopic analyses and studies on respective interaction of cyanuric acid and uric acid with bovine serum albumin and melamine.

Spectroscopic analyses on interaction of melamine, cyanuric acid and uric acid with DNA

Spectroscopic investigation on interaction and sonodynamic damage of Riboflavin to DNA under ultrasonic irradiation by using Methylene Blue as fluorescent probe

Interaction and sonodynamic damage activity of acridine red (AD-R) to bovine serum albumin (BSA)

Fenthion and parathion are two representative kinds of organophosphorus pesticides and widely used in agriculture. They are directly or indirectly released into the atmosphere by spraying or volatilization processes. However, their heterogeneous reactivity toward OH radicals has not yet been well understood. Therefore, this work investigated the heterogeneous kinetics of the OH-initiated degradation of surface-bound fenthion and parathion using a flow reactor. The results showed that OH radicals played an important role in the atmospheric degradation of fenthion and parathion. Their average rate constants were (7.20 ± 0.77) × 10−12 and (10.40 ± 0.60) × 10−12 cm3 molecule−1 s−1 at a relative humidity (RH) and temperature of 35% and 20 °C, respectively, suggesting that they have relatively short lifetimes in the atmosphere. In addition, a negative RH dependence and a positive temperature dependence of the rate constants were observed. The Arrhenius expressions of fenthion and parathion were k2 = (1.34 ± 0.48) × 10−9exp[−(1432.59 ± 105.29)/T] and k2 = (1.96 ± 1.38) × 10−9exp[−(1619.98 ± 222.02)/T], respectively, and their overall activation energy was estimated to be (11.88 ± 0.87) and (13.48 ± 1.83) kJ mol−1. The experimental results will update the kinetic data of fenthion and parathion in the atmosphere and be helpful to further understand their atmospheric transportation processes. 

Heterogeneous kinetics of the OH-initiated degradation of fenthion and parathion.

Dandan Chen

Papers

Spectroscopic analyses and studies on respective interaction of cyanuric acid and uric acid with bovine serum albumin and melamine.

Spectroscopic analyses on interaction of melamine, cyanuric acid and uric acid with DNA

Spectroscopic investigation on interaction and sonodynamic damage of Riboflavin to DNA under ultrasonic irradiation by using Methylene Blue as fluorescent probe

Interaction and sonodynamic damage activity of acridine red (AD-R) to bovine serum albumin (BSA)

Heterogeneous kinetics of the OH-initiated degradation of fenthion and parathion.