Dania O. Govea-Alonso

TL;DR: A compilation of useful bioinformatics tools for vaccine development is presented in this paper, where the most advantageous online immunological software and searchable tools are presented, in order to facilitate the design and development of vaccines.

TL;DR: In this article, a synthetic gene encoding a C4V3 recombinant protein, known to induce systemic and mucosal immune responses in mammalian systems, has been introduced into tobacco chloroplasts to yield high levels of expression.

TL;DR: A chimeric protein targeting Angiotensin II via genetic fusion to a nucleocapsid antigen from Hepatitis B virus, serving as a carrier, is designed, and this candidate immunogen designated as HBcAgII has been expressed in the alga specie Chlamydomonas reinhardtii,serving as an attractive vaccine expression system and delivery host.

TL;DR: The LTB-EBOV protein was expressed in plant tissues at levels up to 14.7 µg/g fresh leaf tissue and proven to be immunogenic in BALB/c mice when administered by either subcutaneous or oral routes and IgA and IgG responses were induced following the oral immunization.

TL;DR: Efforts conducted by a number of research groups to develop vaccines as a mean to fight rabies, cysticercosis, dengue, and helminthiasis are emphasized, and future perspectives are identified, such as the need to develop vaccination models for more than ten pathologies through a plant-based biotechnological approach.