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Daniel A. Fletcher

Researcher at University of California, Berkeley

Publications -  246
Citations -  17323

Daniel A. Fletcher is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: Cytoskeleton & Actin. The author has an hindex of 60, co-authored 226 publications receiving 14283 citations. Previous affiliations of Daniel A. Fletcher include Lawrence Berkeley National Laboratory & University of California.

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Cell mechanics and the cytoskeleton

TL;DR: An important insight emerging from this work is that long-lived cytoskeletal structures may act as epigenetic determinants of cell shape, function and fate.
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Mobile phone based clinical microscopy for global health applications.

TL;DR: A telemedicine system for global healthcare via mobile phone – offering inexpensive brightfield and fluorescence microscopy integrated with automated image analysis – is expected to provide an important tool for disease diagnosis and screening, particularly in the developing world and rural areas where laboratory facilities are scarce but mobile phone infrastructure is extensive.
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Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis.

TL;DR: This work has developed a technique to observe live infected organs and revealed a complex differentiation pathway that facilitates bacterial persistence in the urinary tract.
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Tissue Geometry Determines Sites of Mammary Branching Morphogenesis in Organotypic Cultures

TL;DR: The results reveal that tissue geometry can control organ morphogenesis by defining the local cellular microenvironment, a finding that has relevance to control of invasion and metastasis.
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Use the force: membrane tension as an organizer of cell shape and motility.

TL;DR: Current understanding of how changes in PM tension regulate cell shape and movement is reviewed, as well as how cells sense PM tension.