D
Daniel A. Fletcher
Researcher at University of California, Berkeley
Publications - 246
Citations - 17323
Daniel A. Fletcher is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: Cytoskeleton & Actin. The author has an hindex of 60, co-authored 226 publications receiving 14283 citations. Previous affiliations of Daniel A. Fletcher include Lawrence Berkeley National Laboratory & University of California.
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Journal ArticleDOI
Cell mechanics and the cytoskeleton
TL;DR: An important insight emerging from this work is that long-lived cytoskeletal structures may act as epigenetic determinants of cell shape, function and fate.
Journal ArticleDOI
Mobile phone based clinical microscopy for global health applications.
David N. Breslauer,Robi N. Maamari,Neil A. Switz,Wilbur A. Lam,Wilbur A. Lam,Daniel A. Fletcher +5 more
TL;DR: A telemedicine system for global healthcare via mobile phone – offering inexpensive brightfield and fluorescence microscopy integrated with automated image analysis – is expected to provide an important tool for disease diagnosis and screening, particularly in the developing world and rural areas where laboratory facilities are scarce but mobile phone infrastructure is extensive.
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Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis.
Sheryl S. Justice,Chia S. Hung,Julie A. Theriot,Daniel A. Fletcher,Gregory G. Anderson,Matthew J. Footer,Scott J. Hultgren +6 more
TL;DR: This work has developed a technique to observe live infected organs and revealed a complex differentiation pathway that facilitates bacterial persistence in the urinary tract.
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Tissue Geometry Determines Sites of Mammary Branching Morphogenesis in Organotypic Cultures
Celeste M. Nelson,Martijn M. VanDuijn,Martijn M. VanDuijn,Jamie L. Inman,Jamie L. Inman,Daniel A. Fletcher,Daniel A. Fletcher,Mina J. Bissell,Mina J. Bissell +8 more
TL;DR: The results reveal that tissue geometry can control organ morphogenesis by defining the local cellular microenvironment, a finding that has relevance to control of invasion and metastasis.
Journal ArticleDOI
Use the force: membrane tension as an organizer of cell shape and motility.
TL;DR: Current understanding of how changes in PM tension regulate cell shape and movement is reviewed, as well as how cells sense PM tension.