D
Daniel Aeschlimann
Researcher at Cardiff University
Publications - 80
Citations - 6853
Daniel Aeschlimann is an academic researcher from Cardiff University. The author has contributed to research in topics: Tissue transglutaminase & Ataxia. The author has an hindex of 40, co-authored 78 publications receiving 6525 citations. Previous affiliations of Daniel Aeschlimann include Lund University & Arthritis Research UK.
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Journal ArticleDOI
New strategy for chemical modification of hyaluronic acid: preparation of functionalized derivatives and their use in the formation of novel biocompatible hydrogels.
Paul Bulpitt,Daniel Aeschlimann +1 more
TL;DR: A versatile method for chemical crosslinking high-molecular-weight hyaluronic acid under physiological conditions yielding biocompatible and biodegradable hydrogels is developed.
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Cartilage matrix proteins. An acidic oligomeric protein (COMP) detected only in cartilage.
E Hedbom,Per Antonsson,A. Hjerpe,Daniel Aeschlimann,Mats Paulsson,E. Rosa-Pimentel,Yngve Sommarin,Mikael Wendel,Åke Oldberg,Dick Heinegård +9 more
TL;DR: An Mr = 524,000 oligomeric protein was isolated from bovine cartilage and designated COMP (Cartilage Oligomeric Matrix Protein), which is markedly anionic and shows a preferential localization to the territorial matrix surrounding the chondrocytes.
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Transglutaminases: protein cross-linking enzymes in tissues and body fluids.
Daniel Aeschlimann,Mats Paulsson +1 more
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Protein crosslinking in assembly and remodelling of extracellular matrices: the role of transglutaminases.
TL;DR: The role of transglutaminases in extracellular matrix crosslinking is discussed with a focus on the multifunctional enzyme tissue transGLutaminase, which is implicated in a number of pathological conditions including fibrosis, artherosclerosis, neurodegenerative diseases, celiac disease, and cancer metastasis.
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Gluten sensitivity: from gut to brain
Marios Hadjivassiliou,David S Sanders,Richard A. Grünewald,Nicola Woodroofe,Sabrina Boscolo,Daniel Aeschlimann +5 more
TL;DR: The range of neurological manifestations of gluten sensitivity is reviewed and recent advances in the diagnosis and understanding of the pathophysiological mechanisms underlying neurological dysfunction related to gluten sensitivity are discussed.